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    DENND4B DENN domain containing 4B [ Sus scrofa (pig) ]

    Gene ID: 100157148, updated on 17-Aug-2024

    Summary

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    Official Symbol
    DENND4Bprovided by VGNC
    Official Full Name
    DENN domain containing 4Bprovided by VGNC
    Primary source
    VGNC:VGNC:87252
    See related
    Ensembl:ENSSSCG00000006568
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in spleen (RPKM 12.4), psoas major muscle (RPKM 9.8) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See DENND4B in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 4 NC_010446.5 (95745878..95762192)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 4 NC_010446.4 (104648243..104664335)

    Chromosome 4 - NC_010446.5Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 1 Neighboring gene CREB regulated transcription coactivator 2 Neighboring gene GATA zinc finger domain containing 2B Neighboring gene solute carrier family 27 member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of Rab protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DENN domain-containing protein 4B
    Names
    DENN/MADD domain containing 4B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010446.5 Reference Sscrofa11.1 Primary Assembly

      Range
      95745878..95762192
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013997083.2 → XP_013852537.1  DENN domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    2. XM_021089799.1 → XP_020945458.1  DENN domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A287A5Y5, A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    3. XM_021089798.1 → XP_020945457.1  DENN domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A287A5Y5, A0A4X1VZX5
      Related
      ENSSSCP00000039228.3, ENSSSCT00000051089.3
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    4. XM_013997082.2 → XP_013852536.1  DENN domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    5. XM_021089796.1 → XP_020945455.1  DENN domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    6. XM_005663407.3 → XP_005663464.2  DENN domain-containing protein 4B isoform X1

      UniProtKB/TrEMBL
      A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    7. XM_003481445.4 → XP_003481493.3  DENN domain-containing protein 4B isoform X2

      UniProtKB/TrEMBL
      A0A287A5Y5, A0A4X1VZX5
      Conserved Domains (5) summary
      smart00801
      Location:563 → 636
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:191 → 279
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      sd00004
      Location:813 → 842
      PPR; PPR repeat [structural motif]
      pfam02141
      Location:313 → 497
      DENN; DENN (AEX-3) domain
      cl25449
      Location:811 → 851
      PPR_2; PPR repeat family

    RNA

    1. XR_002343434.1 RNA Sequence

    2. XR_002343435.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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