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    Nkx2-2os NK2 homeobox 2, opposite strand [ Mus musculus (house mouse) ]

    Gene ID: 100313531, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Nkx2-2osprovided by MGI
    Official Full Name
    NK2 homeobox 2, opposite strandprovided by MGI
    Primary source
    MGI:MGI:3652259
    See related
    Ensembl:ENSMUSG00000086509 AllianceGenome:MGI:3652259
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm14112; Nkx2-2as; Nkx2.2AS
    Summary
    Acts upstream of or within positive regulation of gene expression and positive regulation of oligodendrocyte differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Nkx2-2os in Genome Data Viewer
    Location:
    2 G2; 2 72.63 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (147026003..147173601)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (147184083..147331681)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene NK2 homeobox 2 Neighboring gene predicted gene, 57697 Neighboring gene predicted gene 14116 Neighboring gene RIKEN cDNA 6430503K07 gene Neighboring gene Nkx2-2 Hedgehog-responsive enhancer Neighboring gene STARR-seq mESC enhancer starr_05959 Neighboring gene predicted gene, 39955 Neighboring gene STARR-seq mESC enhancer starr_05960 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene paired box 1 divergent transcript Neighboring gene paired box 1 Neighboring gene STARR-seq mESC enhancer starr_05961 Neighboring gene predicted gene, 39956

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Nkx2.2 antisense RNA overexpression enhanced oligodendrocytic differentiation. Tochitani S, et al. Biochem Biophys Res Commun, 2008 Aug 8. PMID 18538132
    2. lncRNAdb: a reference database for long noncoding RNAs. Amaral PP, et al. Nucleic Acids Res, 2011 Jan. PMID 21112873, Free PMC Article
    3. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Other Names

    • NK2 transcription factor related, locus 2, antisense

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of oligodendrocyte differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of oligodendrocyte differentiation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_030769.3 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK045921, AL805918
      Related
      ENSMUST00000136998.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      147026003..147173601
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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