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    Tent5d terminal nucleotidyltransferase 5D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 302368, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tent5dprovided by RGD
    Official Full Name
    terminal nucleotidyltransferase 5Dprovided by RGD
    Primary source
    RGD:1559589
    See related
    EnsemblRapid:ENSRNOG00000023637 AllianceGenome:RGD:1559589
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam46d; RGD1559589
    Summary
    Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in mRNA stabilization. Orthologous to human TENT5D (terminal nucleotidyltransferase 5D). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward (RPKM 24.0) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tent5d in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (76974069..77042306)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (72901287..72974562)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (78911641..78994467)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene forkhead box N2, pseudogene 1 Neighboring gene T-box transcription factor 22 Neighboring gene charged multivesicular body protein 1B2 Neighboring gene WASP family member 1 like Neighboring gene igE-binding protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma. Mroczek S, et al. Nat Commun, 2017 Sep 20. PMID 28931820, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables poly(A) RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables poly(A) RNA polymerase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA stabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    terminal nucleotidyltransferase 5D
    Names
    family with sequence similarity 46, member D
    NP_001100406.1
    XP_006257243.1
    XP_008771557.1
    XP_008771560.1
    XP_017457449.1
    XP_017457453.1
    XP_038955514.1
    XP_063135963.1
    XP_063135964.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106936.2 → NP_001100406.1  terminal nucleotidyltransferase 5D

      See identical proteins and their annotated locations for NP_001100406.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    2. NM_001433958.1 → NP_001420887.1  terminal nucleotidyltransferase 5D

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      76974069..77042306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008773338.4 → XP_008771560.1  terminal nucleotidyltransferase 5D isoform X1

      See identical proteins and their annotated locations for XP_008771560.1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    2. XM_063279893.1 → XP_063135963.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4

    3. XM_063279894.1 → XP_063135964.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4

    4. XM_008773335.4 → XP_008771557.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    5. XM_039099586.2 → XP_038955514.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    6. XM_017601964.3 → XP_017457453.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Related
      ENSRNOP00000104114.1, ENSRNOT00000140006.1
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    7. XM_017601960.3 → XP_017457449.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Related
      ENSRNOP00000089113.1, ENSRNOT00000108845.2
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase

    8. XM_006257181.5 → XP_006257243.1  terminal nucleotidyltransferase 5D isoform X1

      UniProtKB/TrEMBL
      A6IV72, D4A3M4
      Related
      ENSRNOP00000101276.1, ENSRNOT00000167030.1
      Conserved Domains (1) summary
      pfam07984
      Location:9 → 326
      NTP_transf_7; Nucleotidyltransferase
    Nucleotide Protein Strain
    Heading Accession and Version

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