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    Nipsnap3b nipsnap homolog 3B [ Mus musculus (house mouse) ]

    Gene ID: 66536, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nipsnap3bprovided by MGI
    Official Full Name
    nipsnap homolog 3Bprovided by MGI
    Primary source
    MGI:MGI:1913786
    See related
    Ensembl:ENSMUSG00000015247 AllianceGenome:MGI:1913786
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nipsnap3a; 2700063N13Rik
    Summary
    Predicted to be involved in mitophagy. Located in mitochondrion. Is expressed in cortical plate and genitourinary system. Orthologous to several human genes including NIPSNAP3A (nipsnap homolog 3A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver adult (RPKM 34.0), large intestine adult (RPKM 32.9) and 28 other tissues See more
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    Genomic context

    See Nipsnap3b in Genome Data Viewer
    Location:
    4 B2; 4 28.57 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (53011932..53022060)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (53011880..53022060)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily D member 1 Neighboring gene nipsnap homolog 3A Neighboring gene STARR-positive B cell enhancer ABC_E6179 Neighboring gene ATP-binding cassette, sub-family A member 1 Neighboring gene predicted gene, 54225

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mitophagy IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein NipSnap homolog 3B
    Names
    NIPSNAP-related protein
    nipsnap homolog 3A
    protein NipSnap homolog 3A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347099.2NP_001334028.1  protein NipSnap homolog 3B isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AL772397
      Consensus CDS
      CCDS84730.1
      UniProtKB/TrEMBL
      B1AWZ5
      Related
      ENSMUSP00000103292.4, ENSMUST00000107665.4
    2. NM_025623.4NP_079899.1  protein NipSnap homolog 3B isoform 1

      See identical proteins and their annotated locations for NP_079899.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AL772397
      Consensus CDS
      CCDS18186.1
      UniProtKB/Swiss-Prot
      B1AWZ4, Q8VHX9, Q9CQE1
      Related
      ENSMUSP00000015391.4, ENSMUST00000015391.10
      Conserved Domains (1) summary
      pfam07978
      Location:146245
      NIPSNAP; NIPSNAP

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      53011932..53022060
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)