U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nup62cl nucleoporin 62 C-terminal like [ Mus musculus (house mouse) ]

    Gene ID: 279706, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Nup62clprovided by MGI
    Official Full Name
    nucleoporin 62 C-terminal likeprovided by MGI
    Primary source
    MGI:MGI:2685565
    See related
    Ensembl:ENSMUSG00000072944 AllianceGenome:MGI:2685565
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm719
    Summary
    Predicted to enable phospholipid binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to be part of nuclear pore central transport channel. Orthologous to human NUP62CL (nucleoporin 62 C-terminal like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in placenta adult (RPKM 71.0) and testis adult (RPKM 5.1) See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Nup62cl in Genome Data Viewer
    Location:
    X F1; X 61.35 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (138907551..138963456, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (140006802..140062707, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene microrchidia 4 Neighboring gene predicted gene, 52431 Neighboring gene NMD3 homolog pseudogene Neighboring gene RNA binding motif protein 41 Neighboring gene STARR-seq mESC enhancer starr_48000 Neighboring gene dynein axonemal assembly factor 6 Neighboring gene predicted gene, 39537

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance. Zhang W, et al. Cell Rep, 2023 Dec 26. PMID 38060382
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear pore central transport channel IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    nucleoporin-62 C-terminal-like protein
    Names
    novel Nsp1-like C-terminal region containing protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081668.1 → NP_001075137.1  nucleoporin-62 C-terminal-like protein

      See identical proteins and their annotated locations for NP_001075137.1

      Status: VALIDATED

      Source sequence(s)
      BC100367, CJ067064
      Consensus CDS
      CCDS53206.1
      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Related
      ENSMUSP00000098772.3, ENSMUST00000101212.9
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      138907551..138963456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528566.1 → XP_006528629.1  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528629.1

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    2. XM_006528567.2 → XP_006528630.1  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528630.1

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    3. XM_017318521.3 → XP_017174010.1  nucleoporin-62 C-terminal-like protein isoform X2

      UniProtKB/TrEMBL
      A2AG11
      Conserved Domains (1) summary
      pfam05064
      Location:65 → 137
      Nsp1_C; Nsp1-like C-terminal region

    4. XM_006528561.4 → XP_006528624.2  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528624.2

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    5. XM_006528565.3 → XP_006528628.1  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528628.1

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    6. XM_006528563.4 → XP_006528626.2  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528626.2

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region

    7. XM_006528562.5 → XP_006528625.2  nucleoporin-62 C-terminal-like protein isoform X1

      See identical proteins and their annotated locations for XP_006528625.2

      UniProtKB/TrEMBL
      A2AG10, A2AG11
      Conserved Domains (2) summary
      TIGR02168
      Location:105 → 266
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05064
      Location:65 → 179
      Nsp1_C; Nsp1-like C-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools