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    MEIS2 Meis homeobox 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 539573, updated on 29-Jan-2025

    Summary

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    Official Symbol
    MEIS2provided by VGNC
    Official Full Name
    Meis homeobox 2provided by VGNC
    Primary source
    VGNC:VGNC:31382
    See related
    BGD:BT21371; Ensembl:ENSBTAG00000065193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    human mouse all
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    Genomic context

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    See MEIS2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (32547561..32771695, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101904022 Neighboring gene uncharacterized LOC104973117 Neighboring gene uncharacterized LOC104973118 Neighboring gene small nucleolar RNA U13 Neighboring gene transmembrane and coiled-coil domains 5A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139739

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in animal organ morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in embryonic pattern specification IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in eye development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    homeobox protein Meis2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191269.2 → NP_001178198.1  homeobox protein Meis2

      See identical proteins and their annotated locations for NP_001178198.1

      Status: VALIDATED

      Source sequence(s)
      EE234723, EH147455, NKLS02000010
      UniProtKB/TrEMBL
      A0A3Q1LHM6
      Conserved Domains (2) summary
      pfam05920
      Location:294 → 333
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:110 → 193
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      32547561..32771695 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024997745.2 → XP_024853513.1  homeobox protein Meis2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LHM6
      Conserved Domains (2) summary
      pfam05920
      Location:294 → 333
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:110 → 193
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    2. XM_024997744.2 → XP_024853512.1  homeobox protein Meis2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LHM6
      Conserved Domains (3) summary
      pfam05920
      Location:293 → 332
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:109 → 192
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1
      cl25764
      Location:334 → 462
      PAT1; Topoisomerase II-associated protein PAT1

    3. XM_024997750.2 → XP_024853518.1  homeobox protein Meis2 isoform X7

      Conserved Domains (3) summary
      pfam07271
      Location:288 → 369
      Cytadhesin_P30; Cytadhesin P30/P32
      pfam05920
      Location:206 → 245
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:22 → 105
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    4. XM_024997748.2 → XP_024853516.1  homeobox protein Meis2 isoform X5

      UniProtKB/TrEMBL
      F1MNA3
      Conserved Domains (2) summary
      pfam05920
      Location:294 → 333
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:110 → 194
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    5. XM_024997746.2 → XP_024853514.1  homeobox protein Meis2 isoform X3

      UniProtKB/TrEMBL
      F1MNA3
      Conserved Domains (2) summary
      pfam05920
      Location:294 → 333
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:110 → 194
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    6. XM_024997747.2 → XP_024853515.1  homeobox protein Meis2 isoform X4

      UniProtKB/TrEMBL
      F1MNA3
      Related
      ENSBTAP00070042835.1, ENSBTAT00070070354.1
      Conserved Domains (2) summary
      pfam05920
      Location:293 → 332
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:109 → 193
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    7. XM_024997749.2 → XP_024853517.1  homeobox protein Meis2 isoform X6

      UniProtKB/TrEMBL
      F1MNA3
      Conserved Domains (2) summary
      pfam05920
      Location:293 → 332
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:109 → 193
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001076175.1: Suppressed sequence

      Description
      NM_001076175.1: This RefSeq was temporarily suppressed because the CDS was partial.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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