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    RFC5 replication factor C subunit 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 508389, updated on 30-Jan-2025

    Summary

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    Official Symbol
    RFC5provided by VGNC
    Official Full Name
    replication factor C subunit 5provided by VGNC
    Primary source
    VGNC:VGNC:33889
    See related
    BGD:BT20683; EnsemblRapid:ENSBTAG00070027529
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RFC5 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (57183195..57194572, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene V-set and immunoglobulin domain containing 10 Neighboring gene WD repeat and SOCS box containing 2 Neighboring gene kinase suppressor of ras 2 Neighboring gene U6 spliceosomal RNA Neighboring gene nitric oxide synthase 1 Neighboring gene uncharacterized LOC132342620

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA clamp loader activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA-templated DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DNA replication factor C complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    replication factor C subunit 5
    Names
    replication factor C (activator 1) 5, 36.5kDa
    replication factor C 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075358.1 → NP_001068826.1  replication factor C subunit 5

      See identical proteins and their annotated locations for NP_001068826.1

      Status: PROVISIONAL

      Source sequence(s)
      BC108105
      UniProtKB/TrEMBL
      A0A3Q1LY33, Q32PI3
      Related
      ENSBTAP00070037508.1, ENSBTAT00070062660.1
      Conserved Domains (4) summary
      cd00009
      Location:34 → 175
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      TIGR00678
      Location:43 → 215
      holB; DNA polymerase III, delta' subunit
      pfam08542
      Location:257 → 289
      Rep_fac_C; Replication factor C C-terminal domain
      pfam16193
      Location:191 → 219
      AAA_assoc_2; AAA C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      57183195..57194572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875929.1 → XP_059731912.1  replication factor C subunit 5 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LY33, A0A3Q1N9R6
      Related
      ENSBTAP00070037520.1, ENSBTAT00070062676.1

    2. XM_059875930.1 → XP_059731913.1  replication factor C subunit 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LY33
    Nucleotide Protein Strain
    Heading Accession and Version

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