LGALS1 galectin 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: LGALS1provided by VGNC
Official Full Name: galectin 1provided by VGNC
Primary source: VGNC:VGNC:30850
See related: Ensembl:ENSBTAG00000015089
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (109512513..109515793)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest that galectin-1 and VEGFR-2 are expressed at mid-luteal stages in luteal cells of corpus luteum; galectin-1 binds directly to asparagine-linked glycans (N-glycans) on VEGFR-2 in luteal cells.
Title: The luteotrophic function of galectin-1 by binding to the glycans on vascular endothelial growth factor receptor-2 in bovine luteal cells.
The relative abundance of PIBF, LGALS1, LGALS3, LGALS3BP, and LGALS9 mRNA would display a differential expression pattern in the endometrium.
Title: Endometrial expression of progesterone-induced blocking factor and galectins-1, -3, -9, and -3 binding protein in the luteal phase and early pregnancy in cattle.
The binding affinity and specificity of galectin-1 for eight different beta-galactosyl terminal disaccharides was studied using molecular-dynamics simulations.
Title: Disaccharide binding to galectin-1: free energy calculations and molecular recognition mechanism.

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General gene information

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Markers

MARC_5821-5822:997299333:3 (e-PCR)
- UniSTS:269582

WI-18867 (e-PCR)
- UniSTS:12186

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbohydrate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables laminin binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in collagen-containing extracellular matrix	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: galectin-1

Names: 14 kDa lectin; S-Lac lectin 1; beta-galactoside-binding lectin L-14-I; gal-1; galaptin; lactose-binding lectin 1; lectin galactoside-binding soluble 1; lectin, galactoside-binding, soluble, 1 (galectin 1)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.