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    PDXK pyridoxal kinase [ Bos taurus (domestic cattle) ]

    Gene ID: 514168, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PDXKprovided by VGNC
    Official Full Name
    pyridoxal kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:50243
    See related
    BGD:BT29797; EnsemblRapid:ENSBTAG00070033379
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PDXK in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (143782398..143813210)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor 2 binding protein Neighboring gene ribosomal RNA processing 1B Neighboring gene cystatin B (stefin B) Neighboring gene cystatin B (stefin B)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC152058

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables pyridoxal kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in pyridoxal 5'-phosphate salvage IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyridoxal kinase
    Names
    pyridoxal (pyridoxine, vitamin B6) kinase
    pyridoxine kinase
    NP_001069119.1
    XP_024840164.1
    XP_059737108.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075651.2 → NP_001069119.1  pyridoxal kinase

      Status: PROVISIONAL

      Source sequence(s)
      BC122793
      UniProtKB/Swiss-Prot
      Q0II59
      UniProtKB/TrEMBL
      A0AAA9RZI6
      Conserved Domains (1) summary
      cl00192
      Location:6 → 304
      ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      143782398..143813210
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881125.1 → XP_059737108.1  pyridoxal kinase isoform X2

      UniProtKB/TrEMBL
      A0AAA9SCI1
      Related
      ENSBTAP00070046014.1, ENSBTAT00070075390.1

    2. XM_024984396.2 → XP_024840164.1  pyridoxal kinase isoform X1

      UniProtKB/TrEMBL
      A0AAA9TN89
      Related
      ENSBTAP00070045985.1, ENSBTAT00070075355.1
      Conserved Domains (1) summary
      cl00192
      Location:30 → 304
      ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0II59.1 GenPept UniProtKB/Swiss-Prot:Q0II59

    Gene LinkOut

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