U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Tsp42A Tetraspanin 42A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35515, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Tsp42Aprovided by FlyBase
    Official Full Name
    Tetraspanin 42Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033042
    Locus tag
    Dmel_CG14468
    See related
    AllianceGenome:FB:FBgn0033042
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14468; Dm.Tsp42A; Dmel\CG14468
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Tsp42A in Genome Data Viewer
    Location:
    41F11-41F11; 2-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5795413..5796710)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1682918..1684215)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Zinc transporter 41F Neighboring gene Odorant receptor 42a Neighboring gene Odorant receptor 42b Neighboring gene defective proboscis extension response 12

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Markstein M, et al. Nat Genet, 2008 Apr. PMID 18311141, Free PMC Article
    2. Ecdysis triggering hormone receptors regulate male courtship behavior via antennal lobe interneurons in Drosophila. Deshpande SA, et al. Gen Comp Endocrinol, 2019 Jul 1. PMID 30543770
    3. Involvement of CD9 and PDGFR in migration is evolutionarily conserved from Drosophila glia to human glioma. Jeibmann A, et al. J Neurooncol, 2015 Sep. PMID 26224160
    4. Genomewide analysis of the Drosophila tetraspanins reveals a subset with similar function in the formation of the embryonic synapse. Fradkin LG, et al. Proc Natl Acad Sci U S A, 2002 Oct 15. PMID 12370414, Free PMC Article
    5. The tetraspanin superfamily in insects. Todres E, et al. Insect Mol Biol, 2000 Dec. PMID 11122467

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tetraspanin 42A
    Names
    CG14468-PA
    CG14468-PB
    Tsp42A-PA
    Tsp42A-PB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5795413..5796710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273786.1 → NP_001260715.1  tetraspanin 42A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260715.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ECC3
      Conserved Domains (2) summary
      cd03127
      Location:101 → 185
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:92 → 209
      Tetraspannin; Tetraspanin family

    2. NM_078899.2 → NP_523623.1  tetraspanin 42A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523623.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ECC3
      Related
      FBpp0085381
      Conserved Domains (2) summary
      cd03127
      Location:101 → 185
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:92 → 209
      Tetraspannin; Tetraspanin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1ECC3 Q1ECC3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools