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    ND-B14.5AL NADH dehydrogenase (ubiquinone) B14.5 A subunit-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40477, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ND-B14.5ALprovided by FlyBase
    Official Full Name
    NADH dehydrogenase (ubiquinone) B14.5 A subunit-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037172
    Locus tag
    Dmel_CG6914
    See related
    AllianceGenome:FB:FBgn0037172
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT13913; CG6914; Dmel\CG6914; dNDUFA7B; N4AM
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ND-B14.5AL in Genome Data Viewer
    Location:
    79F2-79F2; 3-47 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (22606369..22607126)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (22599469..22600226)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Thioredoxin reductase 2 Neighboring gene long non-coding RNA:CR46348 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45967 Neighboring gene long non-coding RNA:CR45381

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deficiency of ValRS-m Causes Male Infertility in Drosophila melanogaster. Duan X, et al. Int J Mol Sci, 2024 Jul 8. PMID 39000597, Free PMC Article
    2. Identification of sphingolipid metabolites that induce obesity via misregulation of appetite, caloric intake and fat storage in Drosophila. Walls SM Jr, et al. PLoS Genet, 2013. PMID 24339790, Free PMC Article
    3. Insights from Drosophila on mitochondrial complex I. Rhooms SK, et al. Cell Mol Life Sci, 2020 Feb. PMID 31485716, Free PMC Article
    4. Regulation of Mitochondrial Complex I Biogenesis in Drosophila Flight Muscles. Garcia CJ, et al. Cell Rep, 2017 Jul 5. PMID 28683319, Free PMC Article
    5. Two functionally different mitochondrial phosphate carriers support Drosophila melanogaster OXPHOS throughout distinct developmental stages. Curcio R, et al. Biochim Biophys Acta Mol Cell Res, 2024 Jan. PMID 37898376

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in ATP synthesis coupled electron transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mitochondrial electron transport, NADH to ubiquinone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase (ubiquinone) B14.5 A subunit-like
    Names
    CG6914-PA
    NADH-ubiquinone oxidoreductase subunit B14.5a
    NADH:ubiquinone oxidoreductase B14.5A subunit
    ND-B14.5AL-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      22606369..22607126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141142.2 → NP_649399.1  NADH dehydrogenase (ubiquinone) B14.5 A subunit-like [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649399.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNT3
      Related
      FBpp0078167
      Conserved Domains (1) summary
      pfam07347
      Location:13 → 98
      CI-B14_5a; NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNT3 Q9VNT3

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