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    CG14857 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41791, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG14857provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038262
    Locus tag
    Dmel_CG14857
    See related
    AllianceGenome:FB:FBgn0038262
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14857
    Summary
    Predicted to enable organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport. Predicted to be located in plasma membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to several human genes including SLC22A10 (solute carrier family 22 member 10); SLC22A11 (solute carrier family 22 member 11); and SLC22A12 (solute carrier family 22 member 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG14857 in Genome Data Viewer
    Location:
    88D4-88D4; 3-56 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14801773..14804342)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10627495..10630064)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene bitesize Neighboring gene long non-coding RNA:CR46024 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in organic anion transport  
    involved_in transmembrane transport  
    Component Evidence Code Pubs
    located_in plasma membrane  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG14857-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14801773..14804342
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142135.4 → NP_650392.1  uncharacterized protein Dmel_CG14857 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650392.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V514, Q9VFG0
      Related
      FBpp0082452
      Conserved Domains (2) summary
      cd06174
      Location:126 → 470
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:11 → 509
      2A0119; cation transport protein
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