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    Inos myo-inositol-1-phosphate synthase [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35671, updated on 9-Dec-2024

    Summary

    Official Symbol
    Inosprovided by FlyBase
    Official Full Name
    myo-inositol-1-phosphate synthaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025885
    Locus tag
    Dmel_CG11143
    See related
    AllianceGenome:FB:FBgn0025885
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    bs36h12.y1; CG11143; Dmel\CG11143; INOS
    Summary
    Enables inositol-3-phosphate synthase activity. Predicted to be involved in inositol biosynthetic process. Predicted to be active in cytoplasm. Is expressed in adult head. Used to study azoospermia. Orthologous to human ISYNA1 (inositol-3-phosphate synthase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Inos in Genome Data Viewer
    Location:
    43C3-43C3; 2-56 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7454922..7458874, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3342427..3346379, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Fatty acid 2-hydroxylase Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45320 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables inositol-3-phosphate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables inositol-3-phosphate synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables inositol-3-phosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables inositol-3-phosphate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in inositol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inositol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in inositol biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    myo-inositol-1-phosphate synthase
    Names
    CG11143-PA
    Inos-PA
    myo-inositol-1-phosphate-synthase
    NP_477405.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7454922..7458874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058057.6NP_477405.1  myo-inositol-1-phosphate synthase [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477405.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O97477, Q8IGW1, Q8MR42
      Related
      FBpp0088368
      Conserved Domains (1) summary
      cl00554
      Location:10513
      NAD_binding_5; Myo-inositol-1-phosphate synthase