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    Arl10 ADP-ribosylation factor-like 10 [ Mus musculus (house mouse) ]

    Gene ID: 56795, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Arl10provided by MGI
    Official Full Name
    ADP-ribosylation factor-like 10provided by MGI
    Primary source
    MGI:MGI:1930788
    See related
    Ensembl:ENSMUSG00000025870 AllianceGenome:MGI:1930788
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arm1; Arl10a
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Is expressed in several structures, including brain; gut; hemolymphoid system gland; male reproductive gland or organ; and mesenteric adipose tissue. Orthologous to human ARL10 (ARF like GTPase 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 14.5), whole brain E14.5 (RPKM 14.4) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Arl10 in Genome Data Viewer
    Location:
    13 B1; 13 28.82 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (54722860..54730578)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (54575047..54582765)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53205 Neighboring gene STARR-positive B cell enhancer ABC_E7241 Neighboring gene predicted gene 2830 Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene RIKEN cDNA 4833439L19 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:54666808-54666917 Neighboring gene predicted gene, 24195 Neighboring gene STARR-positive B cell enhancer ABC_E927 Neighboring gene NOP16 nucleolar protein Neighboring gene HIG1 domain family, member 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors. Louro R, et al. Biochem Biophys Res Commun, 2004 Apr 9. PMID 15033445
    2. Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. West DB, et al. PLoS Genet, 2016 Feb. PMID 26839965, Free PMC Article
    3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    4. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC144317

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ADP-ribosylation factor-like protein 10
    Names
    ADP-ribosylation factor-like 10A
    ADP-ribosylation factor-like membrane-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377082.1 → NP_001364011.1  ADP-ribosylation factor-like protein 10 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC155262
      UniProtKB/TrEMBL
      D3Z4X7
      Related
      ENSMUSP00000116506.2, ENSMUST00000156024.2
      Conserved Domains (1) summary
      cl38936
      Location:78 → 186
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. NM_019968.3 → NP_064352.2  ADP-ribosylation factor-like protein 10 isoform 1

      See identical proteins and their annotated locations for NP_064352.2

      Status: VALIDATED

      Source sequence(s)
      AC155262
      Consensus CDS
      CCDS26530.1
      UniProtKB/Swiss-Prot
      Q14C12, Q9QXJ4
      Related
      ENSMUSP00000026988.5, ENSMUST00000026988.11
      Conserved Domains (1) summary
      cl38936
      Location:78 → 236
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      54722860..54730578
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244544.3 → XP_011242846.1  ADP-ribosylation factor-like protein 10 isoform X1

      Conserved Domains (1) summary
      cl38936
      Location:29 → 137
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9QXJ4.2 GenPept UniProtKB/Swiss-Prot:Q9QXJ4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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