U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rida reactive intermediate imine deaminase A homolog [ Mus musculus (house mouse) ]

    Gene ID: 15473, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ridaprovided by MGI
    Official Full Name
    reactive intermediate imine deaminase A homologprovided by MGI
    Primary source
    MGI:MGI:1095401
    See related
    Ensembl:ENSMUSG00000022323 AllianceGenome:MGI:1095401
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HR12; HRP12; Hrsp12
    Summary
    Predicted to enable several functions, including 2-iminobutanoate deaminase activity; RNA endonuclease activity, producing 3'-phosphomonoesters; and identical protein binding activity. Predicted to be involved in negative regulation of epithelial cell proliferation and negative regulation of gene expression. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human RIDA (reactive intermediate imine deaminase A homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in kidney adult (RPKM 155.7), liver adult (RPKM 100.0) and 8 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rida in Genome Data Viewer
    Location:
    15 B3.1; 15 14.34 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (34484168..34495392, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (34484022..34495246, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:34372917-34373070 Neighboring gene predicted gene, 24523 Neighboring gene ribosomal protein L30 Neighboring gene glutamate rich 5 Neighboring gene processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae) Neighboring gene predicted gene, 22208

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 2-iminobutanoate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables 2-iminobutanoate deaminase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables 2-iminopropanoate deaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA endonuclease activity, producing 3'-phosphomonoesters ISO
    Inferred from Sequence Orthology
    more info
     
    enables RNA endonuclease activity, producing 3'-phosphomonoesters ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables cation binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables deaminase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables long-chain fatty acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transition metal ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mRNA destabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA destabilization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of epithelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    2-iminobutanoate/2-iminopropanoate deaminase
    Names
    heat-responsive protein 12
    ribonuclease UK114
    translation inhibitor L-PSP ribonuclease
    NP_032313.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008287.3NP_032313.2  2-iminobutanoate/2-iminopropanoate deaminase

      See identical proteins and their annotated locations for NP_032313.2

      Status: VALIDATED

      Source sequence(s)
      AW045776, BC125592, BU559752
      Consensus CDS
      CCDS27418.1
      UniProtKB/Swiss-Prot
      P52760, Q569N4
      Related
      ENSMUSP00000022946.6, ENSMUST00000022946.6
      Conserved Domains (1) summary
      TIGR00004
      Location:6129
      TIGR00004; reactive intermediate/imine deaminase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      34484168..34495392 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)