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    Insyn2b inhibitory synaptic factor family member 2B [ Mus musculus (house mouse) ]

    Gene ID: 574403, updated on 27-Dec-2024

    Summary

    Official Symbol
    Insyn2bprovided by MGI
    Official Full Name
    inhibitory synaptic factor family member 2Bprovided by MGI
    Primary source
    MGI:MGI:3643491
    See related
    Ensembl:ENSMUSG00000069911 AllianceGenome:MGI:3643491
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm6041; Fam196b; EG574403
    Summary
    Is expressed in gonad; ovary; and testis. Orthologous to human INSYN2B (inhibitory synaptic factor family member 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in whole brain E14.5 (RPKM 1.9), frontal lobe adult (RPKM 1.7) and 13 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Insyn2b in Genome Data Viewer
    Location:
    11 A4; 11 19.72 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (34264822..34372642)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (34314822..34422642)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene forkhead box I1 Neighboring gene dedicator of cyto-kinesis 2 Neighboring gene RIKEN cDNA 4930403D09 gene Neighboring gene STARR-seq mESC enhancer starr_29144 Neighboring gene STARR-seq mESC enhancer starr_29145 Neighboring gene STARR-seq mESC enhancer starr_29147 Neighboring gene STARR-seq mESC enhancer starr_29148 Neighboring gene STARR-seq mESC enhancer starr_29150 Neighboring gene predicted gene, 29887 Neighboring gene predicted gene, 39681

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Clone Names

    • MGC99845

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    INSYN2B protein
    Names
    family with sequence similarity 196, member B
    protein FAM196B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025382.3NP_001020553.1  INSYN2B protein

      See identical proteins and their annotated locations for NP_001020553.1

      Status: VALIDATED

      Source sequence(s)
      AL669849, AL671971
      Consensus CDS
      CCDS36127.1
      UniProtKB/Swiss-Prot
      Q6GQV1
      Related
      ENSMUSP00000129183.2, ENSMUST00000165963.9
      Conserved Domains (1) summary
      pfam15265
      Location:3535
      FAM196; FAM196 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      34264822..34372642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514763.5XP_006514826.1  INSYN2B protein isoform X1

      See identical proteins and their annotated locations for XP_006514826.1

      UniProtKB/Swiss-Prot
      Q6GQV1
      Conserved Domains (1) summary
      pfam15265
      Location:3535
      FAM196; FAM196 family