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    Il9r interleukin 9 receptor [ Mus musculus (house mouse) ]

    Gene ID: 16199, updated on 9-Dec-2024

    Summary

    Official Symbol
    Il9rprovided by MGI
    Official Full Name
    interleukin 9 receptorprovided by MGI
    Primary source
    MGI:MGI:96564
    See related
    Ensembl:ENSMUSG00000020279 AllianceGenome:MGI:96564
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Enables interleukin-9 receptor activity. Acts upstream of or within B cell activation; immunoglobulin mediated immune response; and regulation of protein metabolic process. Located in cell surface and plasma membrane. Is expressed in bone marrow. Orthologous to human IL9R (interleukin 9 receptor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in spleen adult (RPKM 4.9), thymus adult (RPKM 1.8) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Il9r in Genome Data Viewer
    Location:
    11 18.82 cM; 11 A4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (32137544..32155283, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (32187544..32205283, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39676 Neighboring gene predicted gene, 51888 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:32039676-32039863 Neighboring gene predicted gene, 40823 Neighboring gene predicted gene 12109 Neighboring gene STARR-positive B cell enhancer ABC_E730 Neighboring gene small nuclear ribonucleoprotein 25 (U11/U12) Neighboring gene STARR-positive B cell enhancer ABC_E11473 Neighboring gene rhomboid 5 homolog 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC130502

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables interleukin-9 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables interleukin-9 binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables interleukin-9 receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables interleukin-9 receptor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables interleukin-9 receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    interleukin-9 receptor
    Names
    IL-9 receptor
    IL-9R

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134458.1NP_001127930.1  interleukin-9 receptor isoform 1 precursor

      See identical proteins and their annotated locations for NP_001127930.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes a protein isoform (1) that is shorter by 1 amino acid due to use of an alternate splice acceptor site.
      Source sequence(s)
      AL929446
      Consensus CDS
      CCDS48765.1
      UniProtKB/TrEMBL
      A2AVE0, B7ZD65
      Related
      ENSMUSP00000119557.2, ENSMUST00000128311.8
      Conserved Domains (1) summary
      cd00063
      Location:147254
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    2. NM_008374.2NP_032400.1  interleukin-9 receptor isoform 2 precursor

      See identical proteins and their annotated locations for NP_032400.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) encodes a protein isoform (2) that is longer by 1 amino acid due to use of an alternate splice acceptor site.
      Source sequence(s)
      AL929446
      Consensus CDS
      CCDS24517.1
      UniProtKB/Swiss-Prot
      Q01114
      UniProtKB/TrEMBL
      B7ZD65, Q78PA5
      Related
      ENSMUSP00000118204.2, ENSMUST00000145401.8
      Conserved Domains (1) summary
      cd00063
      Location:147253
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      32137544..32155283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514539.3XP_006514602.1  interleukin-9 receptor isoform X6

      See identical proteins and their annotated locations for XP_006514602.1

      UniProtKB/TrEMBL
      A2AVE0, B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:147254
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    2. XM_017314298.2XP_017169787.1  interleukin-9 receptor isoform X4

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:195301
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    3. XM_006514537.3XP_006514600.1  interleukin-9 receptor isoform X3

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:195302
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    4. XM_006514538.4XP_006514601.1  interleukin-9 receptor isoform X5

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:157264
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    5. XM_006514540.4XP_006514603.1  interleukin-9 receptor isoform X7

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:140247
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    6. XM_006514534.4XP_006514597.1  interleukin-9 receptor isoform X2

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:254360
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    7. XM_006514533.4XP_006514596.1  interleukin-9 receptor isoform X1

      UniProtKB/TrEMBL
      B7ZD65
      Conserved Domains (1) summary
      cd00063
      Location:254361
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...