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    Tfip11 tuftelin interacting protein 11 [ Mus musculus (house mouse) ]

    Gene ID: 54723, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tfip11provided by MGI
    Official Full Name
    tuftelin interacting protein 11provided by MGI
    Primary source
    MGI:MGI:1930075
    See related
    Ensembl:ENSMUSG00000029345 AllianceGenome:MGI:1930075
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Srr1; TIP33; Tip39; 2810002G02Rik
    Summary
    Predicted to enable nucleic acid binding activity. Involved in spliceosomal complex disassembly. Located in extracellular matrix. Is expressed in several structures, including foregut; nervous system; nose; submandibular gland primordium; and tooth. Orthologous to human TFIP11 (tuftelin interacting protein 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 25.3), thymus adult (RPKM 19.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tfip11 in Genome Data Viewer
    Location:
    5 F; 5 54.69 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (112474235..112485939)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (112326369..112338073)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6366 Neighboring gene STARR-positive B cell enhancer ABC_E1685 Neighboring gene predicted gene, 46941 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:112714594-112714795 Neighboring gene STARR-positive B cell enhancer ABC_E3600 Neighboring gene protein-tyrosine sulfotransferase 2 Neighboring gene SRR1 domain containing Neighboring gene HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 Neighboring gene coiled-coil domain containing 121, retrogene 3 Neighboring gene predicted gene 20636

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of U2-type post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type post-mRNA release spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type post-mRNA release spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    located_in extracellular matrix IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    tuftelin-interacting protein 11
    Names
    STIP-1
    septin and tuftelin-interacting protein 1
    tuftelin-interacting protein 33
    tuftelin-interacting protein 39
    tuftelin-interacting protein, 39 kD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018783.4NP_061253.2  tuftelin-interacting protein 11

      See identical proteins and their annotated locations for NP_061253.2

      Status: PROVISIONAL

      Source sequence(s)
      AC123848
      Consensus CDS
      CCDS19539.1
      UniProtKB/Swiss-Prot
      Q8VD06, Q9ERA6
      UniProtKB/TrEMBL
      Q3TTV6, Q3UGE9
      Related
      ENSMUSP00000031288.8, ENSMUST00000031288.14
      Conserved Domains (3) summary
      pfam01585
      Location:150194
      G-patch; G-patch domain
      pfam07842
      Location:398667
      GCFC; GC-rich sequence DNA-binding factor-like protein
      pfam12457
      Location:21105
      TIP_N; Tuftelin interacting protein N terminal

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      112474235..112485939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)