ATE1 arginyltransferase [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: ATE1
Official Full Name: arginyltransferase
Primary source: SGD:S000002985
Locus tag: YGL017W
See related: AllianceGenome:SGD:S000002985; FungiDB:YGL017W; VEuPathDB:YGL017W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables arginyl-tRNA--protein transferase activity. Involved in protein arginylation. Located in cytoplasm. Orthologous to human ATE1 (arginyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome VII - NC_001139.9 Genomic Context describing neighboring genes

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A role is identified for Ate1 in modulating the level of topoisomerase II through the cell cycle.
Title: The identification and characterisation of a functional interaction between arginyl-tRNA-protein transferase and topoisomerase II.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables arginyl-tRNA--protein transferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables arginyl-tRNA--protein transferase activity	IDA Inferred from Direct Assay more info	PubMed
enables arginyl-tRNA--protein transferase activity	IEA Inferred from Electronic Annotation more info
enables arginyl-tRNA--protein transferase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasomal protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein arginylation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein arginylation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_011498.1

Arginyl-tRNA-protein transferase; catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway; may have a role in regulating stress response

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