eIF2beta eukaryotic translation initiation factor 2 subunit beta [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: eIF2betaprovided by FlyBase
Official Full Name: eukaryotic translation initiation factor 2 subunit betaprovided by FlyBase
Primary source: FLYBASE:FBgn0004926
Locus tag: Dmel_CG4153
See related: AllianceGenome:FB:FBgn0004926
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG4153; D-eIF2beta; Dmel\CG4153; eIF-2; eIF-2beta; eIF2-beta; Eif2beta; elF2beta; IF2B
Summary: Predicted to enable mRNA binding activity; translation initiation factor activity; and translation initiation factor binding activity. Involved in axon midline choice point recognition. Predicted to be located in cytosol. Predicted to be part of eukaryotic 43S preinitiation complex; eukaryotic translation initiation factor 2 complex; and multi-eIF complex. Is expressed in adult head and organism. Orthologous to human EIF2S2 (eukaryotic translation initiation factor 2 subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (12525093..12526731, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (12518193..12519831, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables translation initiation factor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in axon midline choice point recognition	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in formation of translation preinitiation complex	IBA Inferred from Biological aspect of Ancestor more info
involved_in formation of translation preinitiation complex	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to endoplasmic reticulum stress	HMP more info	PubMed
involved_in translational initiation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of eukaryotic 43S preinitiation complex	ISS Inferred from Sequence or Structural Similarity more info
part_of eukaryotic translation initiation factor 2 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 2 complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of multi-eIF complex	ISS Inferred from Sequence or Structural Similarity more info

Names: CG4153-PA; eIF-2 subunit beta; eIF2beta-PA; eukaryotic initiation factor 2beta

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The following sections contain reference sequences that belong to a specific genome build. Explain