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    csul capsuleen [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36809, updated on 9-Dec-2024

    Summary

    Official Symbol
    csulprovided by FlyBase
    Official Full Name
    capsuleenprovided by FlyBase
    Primary source
    FLYBASE:FBgn0015925
    Locus tag
    Dmel_CG3730
    See related
    AllianceGenome:FB:FBgn0015925
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ART5; CG3730; Csul; dart5; Dart5; DART5; Dmel\CG3730; dprmt5; dPRMT5; JBP1; PRMT5
    Summary
    Enables protein-arginine omega-N symmetric methyltransferase activity. Involved in intracellular mRNA localization; peptidyl-arginine methylation; and pole plasm assembly. Predicted to be active in cytosol and nucleus. Is expressed in embryonic/larval midgut; head mesoderm; organism; ovary; and trunk mesoderm. Orthologous to human PRMT5 (protein arginine methyltransferase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See csul in Genome Data Viewer
    Location:
    53A3-53A3; 2-79 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16264652..16266959)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12152157..12154464)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Cyclic nucleotide-gated ion channel subunit A Neighboring gene fidipidine Neighboring gene Kinesin heavy chain Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in cytosol  
    is_active_in nucleus  

    General protein information

    Preferred Names
    capsuleen
    Names
    CG3730-PA
    CG3730-PB
    capsuleenn
    csul-PA
    csul-PB
    drosophila arginine methyltransferase 5
    NP_477184.1
    NP_725552.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      16264652..16266959
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057836.4 → NP_477184.1  capsuleen, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477184.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O46117, Q8MKK9, Q9U6Y9, Q9V7L8
      UniProtKB/TrEMBL
      E8NH07
      Related
      FBpp0088810
      Conserved Domains (2) summary
      pfam05185
      Location:163 → 589
      PRMT5; PRMT5 arginine-N-methyltransferase
      pfam16950
      Location:165 → 442
      SAMBD; SAM-binding_domain
    2. NM_166158.2 → NP_725552.1  capsuleen, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725552.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH07
      Related
      FBpp0088811
      Conserved Domains (2) summary
      pfam05185
      Location:158 → 584
      PRMT5; PRMT5 arginine-N-methyltransferase
      pfam16950
      Location:160 → 437
      SAMBD; SAM-binding_domain
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