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    Rnf215 ring finger protein 215 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305478, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rnf215provided by RGD
    Official Full Name
    ring finger protein 215provided by RGD
    Primary source
    RGD:1310738
    See related
    EnsemblRapid:ENSRNOG00000004940 AllianceGenome:RGD:1310738
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310738
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Orthologous to human RNF215 (ring finger protein 215). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 102.5), Lung (RPKM 80.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rnf215 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (83230234..83236668)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (79006659..79013091)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (84368440..84374879)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549281 Neighboring gene mitochondrial fission process 1 Neighboring gene SEC14-like lipid binding 2 Neighboring gene uncharacterized LOC134481866 Neighboring gene coiled-coil domain containing 157 Neighboring gene splicing factor 3A subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 215

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107234.1 → NP_001100704.1  RING finger protein 215 precursor

      See identical proteins and their annotated locations for NP_001100704.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473963
      UniProtKB/TrEMBL
      A6IKE9, D3ZNU0
      Related
      ENSRNOP00000006827.2, ENSRNOT00000006827.5
      Conserved Domains (1) summary
      cd16670
      Location:325 → 374
      RING-H2_RNF215; RING finger, H2 subclass, found in RING finger protein 215 (RNF215) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      83230234..83236668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017599223.3 → XP_017454712.1  RING finger protein 215 isoform X2

    2. XM_006251300.4 → XP_006251362.1  RING finger protein 215 isoform X1

      Conserved Domains (1) summary
      pfam13639
      Location:325 → 368
      zf-RING_2; Ring finger domain

    3. XM_063273206.1 → XP_063129276.1  RING finger protein 215 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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