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    CG9582 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9582provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032090
    Locus tag
    Dmel_CG9582
    See related
    AllianceGenome:FB:FBgn0032090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9582
    Summary
    Predicted to enable alpha-ketoglutarate transmembrane transporter activity. Predicted to be involved in mitochondrial alpha-ketoglutarate transmembrane transport. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. Orthologous to human SLC25A21 (solute carrier family 25 member 21). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9582 in Genome Data Viewer
    Location:
    29F8-29F8; 2-34 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9024320..9031836, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9024320..9031836, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Rcd-1 related Neighboring gene long non-coding RNA:CR44352 Neighboring gene Dpr-interacting protein zeta Neighboring gene long non-coding RNA:CR44483 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose. Ji Z, et al. Elife, 2021 Apr 13. PMID 33847264, Free PMC Article
    2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article
    5. A gain-of-function screen for genes that influence axon guidance identifies the NF-kappaB protein dorsal and reveals a requirement for the kinase Pelle in Drosophila photoreceptor axon targeting. Mindorff EN, et al. Genetics, 2007 Aug. PMID 17603113, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alpha-ketoglutarate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial alpha-ketoglutarate transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9582-PA
    CG9582-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9024320..9031836 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298844.1 → NP_001285773.1  uncharacterized protein Dmel_CG9582, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285773.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLF1
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 296
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:17 → 104
      Mito_carr; Mitochondrial carrier protein

    2. NM_135426.3 → NP_609270.1  uncharacterized protein Dmel_CG9582, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609270.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLF1
      Related
      FBpp0079379
      Conserved Domains (2) summary
      PTZ00169
      Location:17 → 296
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:17 → 104
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLF1 Q9VLF1

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