U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG4972 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34388, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG4972provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032217
    Locus tag
    Dmel_CG4972
    See related
    AllianceGenome:FB:FBgn0032217
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4972; Q9VKZ7_DROME
    Summary
    Predicted to be involved in regulation of signal transduction. Located in endomembrane system. Is expressed in several structures, including Malpighian tubule main body primordium; Malpighian tubule primordium; embryonic/larval midgut primordium; ganglia; and gut section. Orthologous to human NCLN (nicalin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG4972 in Genome Data Viewer
    Location:
    31D5-31D6; 2-41 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10314792..10317569)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10314792..10317569)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene lethal (2) SH0834 Neighboring gene Ubiquitin specific protease 14 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ribonucleoside diphosphate reductase large subunit

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation. Kochanova NY, et al. Nucleic Acids Res, 2020 May 7. PMID 32182352, Free PMC Article
    2. On-bead tryptic proteolysis: an attractive procedure for LC-MS/MS analysis of the Drosophila caspase 8 protein complex during immune response against bacteria. Fukuyama H, et al. J Proteomics, 2012 Aug 3. PMID 22450469
    3. Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy. Yatsenko AS, et al. BMC Med, 2020 Jan 21. PMID 31959160, Free PMC Article
    4. Identification of Drosophila centromere associated proteins by quantitative affinity purification-mass spectrometry. Barth TK, et al. Data Brief, 2015 Sep. PMID 26306323, Free PMC Article
    5. Genome features of "Dark-fly", a Drosophila line reared long-term in a dark environment. Izutsu M, et al. PLoS One, 2012. PMID 22432011, Free PMC Article

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG4972-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10314792..10317569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135534.3 → NP_609378.1  uncharacterized protein Dmel_CG4972 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609378.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ34, Q9VKZ7
      Related
      FBpp0079578
      Conserved Domains (1) summary
      cd03882
      Location:121 → 429
      M28_nicalin_like; M28 Zn-Peptidase Nicalin, Nicastrin-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZ34 Q8MZ34
    Q9VKZ7 Q9VKZ7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools