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    CG43795 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740629, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG43795provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0264339
    Locus tag
    Dmel_CG43795
    See related
    AllianceGenome:FB:FBgn0264339
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13552; CG13553; CG13556; CG18678; CG18679; CG34372; CG5357; Dmel\CG43795
    Old locus tag
    CG13552; CG13556; CG18678; CG18679; Dmel_CG13552; Dmel_CG13556; Dmel_CG18678; Dmel_CG18679; Dmel_CG34372; Dmel_CG5357
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1E. Orthologous to human GPR158 (G protein-coupled receptor 158) and GPR179 (G protein-coupled receptor 179). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG43795 in Genome Data Viewer
    Location:
    59E1-59E2; 2-103 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23444137..23491997)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19331660..19379520)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 59a Neighboring gene SKP1-related F Neighboring gene long non-coding RNA:CR43792 Neighboring gene long non-coding RNA:CR43793 Neighboring gene Odorant receptor 59b Neighboring gene Odorant receptor 59c Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genetic RNAi screen for IP₃/Ca²⁺ coupled GPCRs in Drosophila identifies the PdfR as a regulator of insect flight. Agrawal T, et al. PLoS Genet, 2013. PMID 24098151, Free PMC Article
    2. Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila. Chow CY, et al. Hum Mol Genet, 2016 Feb 15. PMID 26662796, Free PMC Article
    3. A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration. Na D, et al. Mol Syst Biol, 2023 Dec 6. PMID 37984409, Free PMC Article
    4. The genetic architecture of larval aggregation behavior in Drosophila. McKinney RM, et al. J Neurogenet, 2021 Sep. PMID 33629904
    5. Genome-Wide Association Analysis of Anoxia Tolerance in Drosophila melanogaster. Campbell JB, et al. G3 (Bethesda), 2019 Sep 4. PMID 31311780, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG43795-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23444137..23491997
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103965.3 → NP_001097435.2  uncharacterized protein Dmel_CG43795 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097435.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DY43
      Conserved Domains (1) summary
      pfam00003
      Location:754 → 995
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8DY43 A8DY43

    Gene LinkOut

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