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    ccb central complex broad [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33096, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ccbprovided by FlyBase
    Official Full Name
    central complex broadprovided by FlyBase
    Primary source
    FLYBASE:FBgn0287645
    Locus tag
    Dmel_CG14579
    See related
    AllianceGenome:FB:FBgn0287645
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CCB; CG14579; Dmel\CG14579
    Summary
    Involved in behavioral response to ethanol and central complex development. Is expressed in DALv2 lineage neurons; embryonic Malpighian tubule; embryonic/larval salivary gland; larval tracheal system; and synaptic neuropil domain. Used to study alcohol use disorder. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ccb in Genome Data Viewer
    Location:
    19F2-19F2; 1-65 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (21193253..21194521)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (21064280..21065548)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene long non-coding RNA:CR45506 Neighboring gene uncharacterized protein Neighboring gene Membrane-bound Notch regulator Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila enhancer-Gal4 lines show ectopic expression during development. Casas-Tintó S, et al. R Soc Open Sci, 2017 Mar. PMID 28405401, Free PMC Article
    2. CCB is Involved in Actin-Based Axonal Transport of Selected Synaptic Proteins. Martin-Peña A, et al. J Neurosci, 2020 Jan 15. PMID 31754011, Free PMC Article
    3. Neuronal control of locomotor handedness in Drosophila. Buchanan SM, et al. Proc Natl Acad Sci U S A, 2015 May 26. PMID 25953337, Free PMC Article
    4. A higher control center of locomotor behavior in the Drosophila brain. Strauss R, et al. J Neurosci, 1993 May. PMID 8478679, Free PMC Article
    5. Distinct memory traces for two visual features in the Drosophila brain. Liu G, et al. Nature, 2006 Feb 2. PMID 16452971

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in behavioral response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in central complex development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    central complex broad
    Names
    CG14579-PA
    ccb-PA
    central-complex-broad

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      21193253..21194521
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134594.2 → NP_608438.1  central complex broad [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608438.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VRF5
      Related
      FBpp0076948
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VRF5 Q9VRF5

    Gene LinkOut

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