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    stil stand still [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36380, updated on 9-Dec-2024

    Summary

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    Official Symbol
    stilprovided by FlyBase
    Official Full Name
    stand stillprovided by FlyBase
    Primary source
    FLYBASE:FBgn0003527
    Locus tag
    Dmel_CG8592
    See related
    AllianceGenome:FB:FBgn0003527
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    152072_at; CG8592; Dmel\CG8592; Stil; Y10276
    Summary
    Enables chromatin binding activity. Involved in several processes, including female sex determination; germ-line sex determination; and positive regulation of DNA-templated transcription. Located in chromatin. Is expressed in germarium; germline cell; gonad; and primary spermatocyte cyst. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See stil in Genome Data Viewer
    Location:
    49B5-49B5; 2-67 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12570367..12571883)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8457872..8459388)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 301a1 Neighboring gene Adenylate kinase 6 Neighboring gene Chloride channel-b Neighboring gene Sin3A Neighboring gene long non-coding RNA:CR30055

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Blocked endocytotic uptake by the oocyte causes accumulation of vitellogenins in the haemolymph of the female-sterile mutants quitPX61 and stand stillPS34 of Drosophila. Gutzeit HO, et al. Cell Tissue Res, 1994 Feb. PMID 8111838
    2. Mutations in the gene stand still disrupt germ cell differentiation in Drosophila ovaries. Mulligan PK, et al. Dev Genet, 1996. PMID 8754283
    3. Comparison of genome architecture at two stages of male germline cell differentiation in Drosophila. Ilyin AA, et al. Nucleic Acids Res, 2022 Apr 8. PMID 35166842, Free PMC Article
    4. PLK4 promotes centriole duplication by phosphorylating STIL to link the procentriole cartwheel to the microtubule wall. Moyer TC, et al. Elife, 2019 May 22. PMID 31115335, Free PMC Article
    5. The Drosophila Sin3 gene encodes a widely distributed transcription factor essential for embryonic viability. Pennetta G, et al. Dev Genes Evol, 1998 Nov. PMID 9799435

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in female sex determination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in female sex differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in germ-line sex determination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oogenesis HMP PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stand still
    Names
    CG8592-PA
    stil-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12570367..12571883
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057404.4 → NP_476752.1  stand still [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476752.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P92189, Q9V6D8
      Related
      FBpp0086938
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P92189.2 P92189

    Gene LinkOut

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