U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UQCR-11L Ubiquinol-cytochrome c reductase 11 kDa subunit-like [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246560, updated on 9-Dec-2024

    Summary

    Official Symbol
    UQCR-11Lprovided by FlyBase
    Official Full Name
    Ubiquinol-cytochrome c reductase 11 kDa subunit-likeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050354
    Locus tag
    Dmel_CG30354
    See related
    AllianceGenome:FB:FBgn0050354
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG30354; Dmel\CG30354; NEST:bs01g03; UCRH
    Summary
    Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to human UQCRH (ubiquinol-cytochrome c reductase hinge protein) and UQCRHL (ubiquinol-cytochrome c reductase hinge protein like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See UQCR-11L in Genome Data Viewer
    Location:
    44E2-44E2; 2-59 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8677219..8677661)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4564724..4565166)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44281 Neighboring gene patched Neighboring gene Acyl-CoA synthetase long-chain Neighboring gene transfer RNA:Leucine-CAG 1-1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to ubiquinol-cytochrome-c reductase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial intermembrane space ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex III ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    Ubiquinol-cytochrome c reductase 11 kDa subunit-like
    Names
    CG30354-PA
    CG30354-PB
    UQCR-11L-PA
    UQCR-11L-PB
    Ubiquinol-cytochrome C reductase complex 11 kDa protein
    Ubiquinol-cytochrome c reductase 11 kDa protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8677219..8677661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273882.1NP_001260811.1  Ubiquinol-cytochrome c reductase 11 kDa subunit-like, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260811.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPY6
      Conserved Domains (1) summary
      pfam02320
      Location:2385
      UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein
    2. NM_165616.3NP_724697.1  Ubiquinol-cytochrome c reductase 11 kDa subunit-like, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724697.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPY6
      Related
      FBpp0087782
      Conserved Domains (1) summary
      pfam02320
      Location:2385
      UCR_hinge; Ubiquinol-cytochrome C reductase hinge protein