CG6345 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG6345provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0037816
Locus tag: Dmel_CG6345
See related: AllianceGenome:FB:FBgn0037816
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 149631_at; Dmel\CG6345
Summary: Predicted to enable N6-isopentenyladenosine methylthiotransferase activity. Predicted to be involved in mitochondrial tRNA modification and regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including Malpighian tubule primordium; anterior endoderm; anterior endoderm anlage; embryonic/larval midgut primordium; and mesoderm. Orthologous to human CDK5RAP1 (CDK5 regulatory subunit associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (10414218..10416046, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (6239940..6241768, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables N6-isopentenyladenosine methylthiotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N6-isopentenyladenosine methylthiotransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables methylthiotransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA modification	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial tRNA modification	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cyclin-dependent protein serine/threonine kinase activity	ISS Inferred from Sequence or Structural Similarity more info
involved_in tRNA modification	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	ISS Inferred from Sequence or Structural Similarity more info

NP_650002.1

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The following sections contain reference sequences that belong to a specific genome build. Explain