U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bbg big bang [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39583, updated on 9-Dec-2024

    Summary

    Official Symbol
    bbgprovided by FlyBase
    Official Full Name
    big bangprovided by FlyBase
    Primary source
    FLYBASE:FBgn0087007
    Locus tag
    Dmel_CG42230
    See related
    AllianceGenome:FB:FBgn0087007
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Bbg; BBG; C96; CG42230; CG9587; CG9598; Dmel\CG42230
    Old locus tag
    Dmel_CG9587; Dmel_CG9598
    Summary
    Involved in border follicle cell migration and imaginal disc-derived wing morphogenesis. Located in apical part of cell; nucleus; and septate junction. Is expressed in several structures, including anlage in statu nascendi; epithelium; follicle cell; gut section; and sensory organ cell. Used to study inflammatory bowel disease. Human ortholog(s) of this gene implicated in asthma; colorectal adenocarcinoma; and prostate cancer. Orthologous to human PDZD2 (PDZ domain containing 2) and IL16 (interleukin 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See bbg in Genome Data Viewer
    Location:
    70D7-70E1; 3-42 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (14412828..14536276, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (14405928..14529376, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45233 Neighboring gene long non-coding RNA:CR46032 Neighboring gene stonewall Neighboring gene long non-coding RNA:CR46031 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Mitochondrial phosphate carrier protein 2

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    big bang
    Names
    C96
    CG42230-PC
    CG42230-PE
    CG42230-PF
    CG42230-PG
    CG42230-PH
    CG42230-PI
    CG42230-PJ
    CG42230-PK
    bbg-PC
    bbg-PE
    bbg-PF
    bbg-PG
    bbg-PH
    bbg-PI
    bbg-PJ
    bbg-PK

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      14412828..14536276 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140447.4NP_648704.2  big bang, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648704.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q83, Q9VUE7
      Conserved Domains (1) summary
      cd00992
      Location:789871
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. NM_001144478.4NP_001137950.1  big bang, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137950.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q80
      Conserved Domains (1) summary
      cd00992
      Location:727809
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    3. NM_001144479.4NP_001137951.1  big bang, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137951.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q80
      Conserved Domains (1) summary
      cd00992
      Location:727809
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    4. NM_140448.3NP_648705.2  big bang, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648705.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q85, Q9VUE8
      Conserved Domains (2) summary
      cd00992
      Location:23312413
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl21478
      Location:10841109
      ATP-synt_B; ATP synthase B/B' CF(0)
    5. NM_001259826.1NP_001246755.1  big bang, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246755.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q85, Q9VUE8
      Conserved Domains (2) summary
      cd00992
      Location:23312413
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl21478
      Location:10841109
      ATP-synt_B; ATP synthase B/B' CF(0)
    6. NM_001144481.2NP_001137953.1  big bang, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137953.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q15K24
      Conserved Domains (3) summary
      cd00992
      Location:15361618
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl21478
      Location:289314
      ATP-synt_B; ATP synthase B/B' CF(0)
      cl21479
      Location:313432
      Cas5_I; CRISPR/Cas system-associated RAMP superfamily protein Cas5
    7. NM_001144477.2NP_001137949.1  big bang, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137949.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q84
      Conserved Domains (1) summary
      cd00992
      Location:795877
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    8. NM_001144480.3NP_001137952.1  big bang, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17Q80
      Conserved Domains (1) summary
      cd00992
      Location:727809
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...