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    dpy dumpy [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318824, updated on 9-Dec-2024

    Summary

    Official Symbol
    dpyprovided by FlyBase
    Official Full Name
    dumpyprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053196
    Locus tag
    Dmel_CG33196
    See related
    AllianceGenome:FB:FBgn0053196
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD02173; CG15637; CG31724; CG31725; CG31726; CG31727; CG31964; CG31965; CG31966; CG31967; CG31968; CG33000; CG33086; CG33196; CR33195; CT35799; Dmel\CG33196; dmFBN2; dp; Dp; DP; Dpy; DPY; l(2)24Fd; Mur24F; olv[D]; Q8IQ18_DROME; SP460
    Summary
    Predicted to be an extracellular matrix structural constituent. Involved in several processes, including chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; and imaginal disc-derived wing morphogenesis. Predicted to be located in extracellular matrix. Is expressed in several structures, including epithelial tube; gut section; longitudinal vein; nephrocyte; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See dpy in Genome Data Viewer
    Location:
    24F4-25A1; 2-13 cM
    Exon count:
    85
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4477462..4614300, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4477462..4614300, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Parkin Interacting Substrate Neighboring gene FIG4 phosphoinositide 5-phosphatase Neighboring gene inebriated Neighboring gene long non-coding RNA:CR43716 Neighboring gene Heterochromatin protein 6 Neighboring gene long non-coding RNA:CR44609 Neighboring gene long non-coding RNA:CR45452

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    dumpy
    Names
    CG33196-PAA
    CG33196-PI
    CG33196-PJ
    CG33196-PM
    CG33196-PO
    CG33196-PP
    CG33196-PQ
    CG33196-PR
    CG33196-PS
    CG33196-PT
    CG33196-PU
    CG33196-PV
    CG33196-PW
    CG33196-PX
    CG33196-PY
    CG33196-PZ
    dpy-PAA
    dpy-PI
    dpy-PJ
    dpy-PM
    dpy-PO
    dpy-PP
    dpy-PQ
    dpy-PR
    dpy-PS
    dpy-PT
    dpy-PU
    dpy-PV
    dpy-PW
    dpy-PX
    dpy-PY
    dpy-PZ
    fibrillin-like
    mucin related 24F

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4477462..4614300 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258947.3NP_001245876.1  dumpy, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245876.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NCR4
      Conserved Domains (8) summary
      PHA03255
      Location:79098078
      PHA03255; BDLF3; Provisional
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1473214967
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1487014966
      Zona_pellucida; Zona pellucida-like domain
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15950
      Location:40884235
      DUF4758; Domain of unknown function (DUF4758)
    2. NM_001273110.1NP_001260039.1  dumpy, isoform X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260039.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCJ8
      Conserved Domains (8) summary
      PHA03255
      Location:79098078
      PHA03255; BDLF3; Provisional
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1445214687
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1459014686
      Zona_pellucida; Zona pellucida-like domain
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15950
      Location:40884235
      DUF4758; Domain of unknown function (DUF4758)
    3. NM_001273109.1NP_001260038.1  dumpy, isoform W [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260038.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBZ4
      Conserved Domains (7) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1764117876
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1777917875
      Zona_pellucida; Zona pellucida-like domain
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15950
      Location:40884235
      DUF4758; Domain of unknown function (DUF4758)
    4. NM_001273108.1NP_001260037.1  dumpy, isoform V [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260037.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB31
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2003120266
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:212247
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2016920265
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1625016410
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1622216287
      YppG; YppG-like protein
      pfam15767
      Location:32113851
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1648116713
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:15431690
      DUF4758; Domain of unknown function (DUF4758)
    5. NM_001273112.1NP_001260041.1  dumpy, isoform Z [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260041.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEI7
      Conserved Domains (6) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1562515860
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1576315859
      Zona_pellucida; Zona pellucida-like domain
      pfam06247
      Location:193335
      Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
      pfam12947
      Location:137166
      EGF_3; EGF domain
    6. NM_001273107.1NP_001260036.1  dumpy, isoform U [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260036.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEI1
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2128421519
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2142221518
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1750317663
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1747517540
      YppG; YppG-like protein
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1773417966
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:40884282
      DUF4758; Domain of unknown function (DUF4758)
    7. NM_001273106.1NP_001260035.1  dumpy, isoform T [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260035.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PC45
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2192722162
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2206522161
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1814618306
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1811818183
      YppG; YppG-like protein
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1837718609
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:40884282
      DUF4758; Domain of unknown function (DUF4758)
    8. NM_001273103.1NP_001260032.1  dumpy, isoform Q [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260032.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB30
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2257622811
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2271422810
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1879518955
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1876718832
      YppG; YppG-like protein
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1902619258
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:40884282
      DUF4758; Domain of unknown function (DUF4758)
    9. NM_001273111.1NP_001260040.1  dumpy, isoform Y [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260040.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PC48
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1772217957
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1786017956
      Zona_pellucida; Zona pellucida-like domain
      pfam06247
      Location:193335
      Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
      pfam09310
      Location:1396614125
      PD-C2-AF1; POU domain, class 2, associating factor 1
      pfam11235
      Location:1394114101
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1391313978
      YppG; YppG-like protein
      pfam15822
      Location:1417214404
      MISS; MAPK-interacting and spindle-stabilizing protein-like
    10. NM_001273101.1NP_001260030.1  dumpy, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260030.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PC41
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2237022605
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2250822604
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1858918749
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1856118626
      YppG; YppG-like protein
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1882019052
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:40884282
      DUF4758; Domain of unknown function (DUF4758)
    11. NM_001258950.1NP_001245879.1  dumpy, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245879.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NE82
      Conserved Domains (6) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:82068441
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:212247
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:83448440
      Zona_pellucida; Zona pellucida-like domain
      pfam06247
      Location:193335
      Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
      pfam12947
      Location:137166
      EGF_3; EGF domain
    12. NM_001273104.1NP_001260033.1  dumpy, isoform R [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260033.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBZ0
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2245722692
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:212247
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2259522691
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1867618836
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1864818713
      YppG; YppG-like protein
      pfam15767
      Location:56376277
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1890719139
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:39694163
      DUF4758; Domain of unknown function (DUF4758)
    13. NM_001273105.1NP_001260034.1  dumpy, isoform S [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260034.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PCJ6
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1826818503
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1840618502
      Zona_pellucida; Zona pellucida-like domain
      pfam06247
      Location:193335
      Plasmod_Pvs28; Plasmodium ookinete surface protein Pvs28
      pfam09310
      Location:1451214671
      PD-C2-AF1; POU domain, class 2, associating factor 1
      pfam11235
      Location:1448714647
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1445914524
      YppG; YppG-like protein
      pfam15822
      Location:1471814950
      MISS; MAPK-interacting and spindle-stabilizing protein-like
    14. NM_001273113.1NP_001260042.1  dumpy, isoform AA [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260042.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PB32
      Conserved Domains (7) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1918719422
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1932519421
      Zona_pellucida; Zona pellucida-like domain
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15950
      Location:40884282
      DUF4758; Domain of unknown function (DUF4758)
    15. NM_001258946.1NP_001245875.1  dumpy, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245875.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NER8
      Conserved Domains (8) summary
      PHA03255
      Location:79098078
      PHA03255; BDLF3; Provisional
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:1526515500
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:1540315499
      Zona_pellucida; Zona pellucida-like domain
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15950
      Location:40884235
      DUF4758; Domain of unknown function (DUF4758)
    16. NM_001273102.1NP_001260031.1  dumpy, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260031.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEH5
      Conserved Domains (10) summary
      smart00179
      Location:255286
      EGF_CA; Calcium-binding EGF-like domain
      smart00241
      Location:2033720572
      ZP; Zona pellucida (ZP) domain
      cd00054
      Location:338373
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00100
      Location:2047520571
      Zona_pellucida; Zona pellucida-like domain
      pfam11235
      Location:1655616716
      Med25_SD1; Mediator complex subunit 25 synapsin 1
      pfam12947
      Location:137166
      EGF_3; EGF domain
      pfam14179
      Location:1652816593
      YppG; YppG-like protein
      pfam15767
      Location:57566396
      DUF4696; Domain of unknown function (DUF4696)
      pfam15822
      Location:1678717019
      MISS; MAPK-interacting and spindle-stabilizing protein-like
      pfam15950
      Location:40884235
      DUF4758; Domain of unknown function (DUF4758)