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    CG32795 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31270, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG32795provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040384
    Locus tag
    Dmel_CG32795
    See related
    AllianceGenome:FB:FBgn0040384
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2716; CG2766; Dmel\CG32795; EG:BACN33B1.2
    Summary
    Involved in defense response to Gram-negative bacterium and positive regulation of innate immune response. Predicted to be active in membrane. Is expressed in adult head. Orthologous to human TMEM120A (transmembrane protein 120A) and TMEM120B (transmembrane protein 120B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG32795 in Genome Data Viewer
    Location:
    3B6-3B6; 1-1.5 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2782906..2790567, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2676939..2684600, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43494 Neighboring gene kin of irre Neighboring gene Syntaxin 4 Neighboring gene uncharacterized protein Neighboring gene white

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Creation of a new system to study insulators in Drosophila melanogaster. Erokhin MM, et al. Dokl Biochem Biophys, 2009 Sep-Oct. PMID 20848905
    2. Molecular and bioinformatic analysis of the FB-NOF transposable element. Badal M, et al. Gene, 2006 Apr 12. PMID 16478650
    3. An FB-NOF mediated duplication of the white gene is responsible for the zeste1 phenotype in some Drosophila melanogaster unstable strains. Badal M, et al. Mol Genet Genomics, 2006 Jan. PMID 16333669
    4. Transcription initiation from within P elements generates hypomorphic mutations in Drosophila melanogaster. LaFave MC, et al. Genetics, 2011 Jul. PMID 21527778, Free PMC Article
    5. Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs. Chetverina D, et al. Nucleic Acids Res, 2008 Feb. PMID 18086699, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium HMP PubMed 
    involved_in positive regulation of innate immune response HMP PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG32795-PA
    CG32795-PB
    CG32795-PC
    CG32795-PD
    CG32795-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2782906..2790567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258580.1 → NP_001245509.1  uncharacterized protein Dmel_CG32795, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
      UniProtKB/TrEMBL
      A4V3W8
      Conserved Domains (1) summary
      pfam07851
      Location:7 → 329
      TMPIT; TMPIT-like protein

    2. NM_166952.1 → NP_726830.1  uncharacterized protein Dmel_CG32795, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726830.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
      UniProtKB/TrEMBL
      A4V3W8
      Related
      FBpp0070469, FBtr0070491
      Conserved Domains (1) summary
      pfam07851
      Location:7 → 329
      TMPIT; TMPIT-like protein

    3. NM_206617.2 → NP_996340.1  uncharacterized protein Dmel_CG32795, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996340.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
      UniProtKB/TrEMBL
      A4V3W8
      Conserved Domains (1) summary
      pfam07851
      Location:7 → 329
      TMPIT; TMPIT-like protein

    4. NM_130673.4 → NP_570029.1  uncharacterized protein Dmel_CG32795, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570029.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
      UniProtKB/TrEMBL
      A4V3W8
      Related
      FBpp0070470
      Conserved Domains (1) summary
      pfam07851
      Location:7 → 329
      TMPIT; TMPIT-like protein

    5. NM_001297905.1 → NP_001284834.1  uncharacterized protein Dmel_CG32795, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284834.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0KHW4, Q9U1M2, Q9W4V5, Q9W4V6
      UniProtKB/TrEMBL
      A4V3W8
      Conserved Domains (1) summary
      pfam07851
      Location:7 → 329
      TMPIT; TMPIT-like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4V3W8 A4V3W8
    Q9U1M2.1 Q9U1M2

    Gene LinkOut

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