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    CG9953 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38763, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9953provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035726
    Locus tag
    Dmel_CG9953
    See related
    AllianceGenome:FB:FBgn0035726
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9953
    Summary
    Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; embryonic/larval garland cell; and mesoderm. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9953 in Genome Data Viewer
    Location:
    65D5-65D5; 3-18 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6969658..6971666)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6962758..6964766)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mis12 Neighboring gene uncharacterized protein Neighboring gene G protein alpha subunit i Neighboring gene long non-coding RNA:CR32385 Neighboring gene long non-coding RNA:CR46000

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Study of tauopathies by comparing Drosophila and human tau in Drosophila. Chen X, et al. Cell Tissue Res, 2007 Jul. PMID 17406902
    2. dTrmt10A impacts Hsp70 chaperone m(6)A levels and the stress response in the Drosophila brain. Perlegos AE, et al. Sci Rep, 2023 Dec 28. PMID 38155219, Free PMC Article
    3. Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. Yu F, et al. J Cell Biol, 2003 Aug 18. PMID 12925708, Free PMC Article
    4. Functional genomic screen identifies novel mediators of collagen uptake. Lee TH, et al. Mol Biol Cell, 2014 Mar. PMID 24403604, Free PMC Article
    5. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Scherzer CR, et al. Hum Mol Genet, 2003 Oct 1. PMID 12915459

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine hydrolase activity HDA PubMed 
    enables serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9953-PA
    NP_648067.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6969658..6971666
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139810.3 → NP_648067.2  uncharacterized protein Dmel_CG9953 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648067.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZM1, Q9VS02
      Related
      FBpp0076608
      Conserved Domains (1) summary
      pfam05577
      Location:61 → 492
      Peptidase_S28; Serine carboxypeptidase S28
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZM1 Q8SZM1
    Q9VS02 Q9VS02

    Gene LinkOut

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