velo veloren [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: veloprovided by FlyBase
Official Full Name: velorenprovided by FlyBase
Primary source: FLYBASE:FBgn0035713
Locus tag: Dmel_CG10107
See related: AllianceGenome:FB:FBgn0035713
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG10107; Dmel\CG10107; Velo
Summary: Predicted to enable SUMO-specific endopeptidase activity and deSUMOylase activity. Involved in neuron projection morphogenesis and positive regulation of defense response to bacterium. Located in cytosol and nucleus. Is expressed in several structures, including antennal primordium; central brain primordium; embryonic central brain neurons; head epidermis primordium; and spermatozoon. Orthologous to human SENP6 (SUMO specific peptidase 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (6744426..6752752, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (6737526..6745852, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables SUMO-specific endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables deSUMOylase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in central nervous system projection neuron axonogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in dendritic spine morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of peptidoglycan recognition protein signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein desumoylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein desumoylation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

Names: CG10107-PA; CG10107-PB; CG10107-PC; CG10107-PD; velo-PA; velo-PB; velo-PC; velo-PD; verloren

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