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    natalisin natalisin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740700, updated on 9-Dec-2024

    Summary

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    Official Symbol
    natalisinprovided by FlyBase
    Official Full Name
    natalisinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0085417
    Locus tag
    Dmel_CG34388
    See related
    AllianceGenome:FB:FBgn0085417
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14842; CG14843; CG34388; Dmel\CG34388; ntl; Ntl; NTL
    Old locus tag
    CG14842; CG14843; Dmel_CG14842; Dmel_CG14843
    Summary
    Involved in male mating behavior. Is expressed in adult brain; adult pars intercerebralis; adult subesophageal zone; anterior ventrolateral protocerebrum; and ganglia. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See natalisin in Genome Data Viewer
    Location:
    88C1-88C1; 3-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (14418593..14421865)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (10244315..10247587)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene scotti Neighboring gene mir-2281 stem loop Neighboring gene crossveinless c Neighboring gene antisense RNA:CR44176 Neighboring gene long non-coding RNA:CR44177 Neighboring gene HTRA2-related serine protease

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PKA-C3 catalytic subunit is required in two pairs of interneurons for successful mating of Drosophila. Cassar M, et al. Sci Rep, 2018 Feb 6. PMID 29410515, Free PMC Article
    2. Natalisin, a tachykinin-like signaling system, regulates sexual activity and fecundity in insects. Jiang H, et al. Proc Natl Acad Sci U S A, 2013 Sep 10. PMID 23980168, Free PMC Article
    3. Neuropeptide Mapping of Dimmed Cells of Adult Drosophila Brain. Diesner M, et al. J Am Soc Mass Spectrom, 2018 May. PMID 29372551
    4. Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila. Lee SH, et al. Commun Biol, 2021 Jun 7. PMID 34099879, Free PMC Article
    5. The gut hormone Allatostatin C/Somatostatin regulates food intake and metabolic homeostasis under nutrient stress. Kubrak O, et al. Nat Commun, 2022 Feb 4. PMID 35121731, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in male mating behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    natalisin
    Names
    CG34388-PC
    CG34388-PD
    natalisin-PC
    natalisin-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      14418593..14421865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104319.2 → NP_001097789.1  natalisin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097789.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V427, Q4V5I3

    2. NM_001170137.1 → NP_001163608.1  natalisin, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163608.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E2QD54, Q4V5I3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E2QD54 E2QD54
    Q2XYC2 Q2XYC2
    Q4V427 Q4V427

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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