Pex14 Peroxin 14 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Pex14provided by FlyBase
Official Full Name: Peroxin 14provided by FlyBase
Primary source: FLYBASE:FBgn0037020
Locus tag: Dmel_CG4289
See related: AllianceGenome:FB:FBgn0037020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG4289; DmelPex14; Dmel\CG4289; PEX14
Summary: Predicted to enable protein transmembrane transporter activity and signaling receptor binding activity. Involved in protein import into peroxisome matrix. Located in peroxisome. Is expressed in adult head; embryonic cortex; mesoderm; organism; and yolk. Used to study peroxisome biogenesis disorder 13A. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 13A. Orthologous to human PEX14 (peroxisomal biogenesis factor 14). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (20778799..20780378)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (20771899..20773478)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables signaling receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in peroxisome organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein import into peroxisome matrix	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein import into peroxisome matrix, docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into peroxisome matrix, docking	IEA Inferred from Electronic Annotation more info
involved_in protein import into peroxisome matrix, docking	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein import into peroxisome matrix, translocation	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein targeting to peroxisome	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of peroxisomal importomer complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in peroxisomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in peroxisomal membrane	IEA Inferred from Electronic Annotation more info
is_active_in peroxisomal membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed
located_in peroxisome	ISS Inferred from Sequence or Structural Similarity more info	PubMed

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain