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    Cep164 centrosomal protein 164 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32563, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cep164provided by FlyBase
    Official Full Name
    centrosomal protein 164provided by FlyBase
    Primary source
    FLYBASE:FBgn0030716
    Locus tag
    Dmel_CG9170
    See related
    AllianceGenome:FB:FBgn0030716
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.214; CEP164; CG9170; Dmel\CG9170
    Summary
    Part of ciliary transition fiber. Is expressed in several structures, including adult antennal sense organ; male germline cell; and scolopidial cilium. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and nephronophthisis 15. Orthologous to human CEP164 (centrosomal protein 164). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cep164 in Genome Data Viewer
    Location:
    14A4-14A5; 1-52 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15977967..15982944, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15872000..15876977, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Odorant receptor 13a Neighboring gene uncharacterized protein Neighboring gene Solute carrier family 25 member 46a Neighboring gene NADH dehydrogenase (ubiquinone) 20 kDa subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila transition fibers are essential for IFT-dependent ciliary elongation but not basal body docking and ciliary budding. Hou Y, et al. Curr Biol, 2023 Feb 27. PMID 36669498
    2. IFT52 plays an essential role in sensory cilia formation and neuronal sensory function in Drosophila. Hou YN, et al. Insect Sci, 2023 Aug. PMID 36326027
    3. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
    4. Components of Intraflagellar Transport Complex A Function Independently of the Cilium to Regulate Canonical Wnt Signaling in Drosophila. Balmer S, et al. Dev Cell, 2015 Sep 28. PMID 26364750, Free PMC Article
    5. Direct Testing for Allele-Specific Expression Differences Between Conditions. León-Novelo L, et al. G3 (Bethesda), 2018 Feb 2. PMID 29167272, Free PMC Article

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of ciliary transition fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    centrosomal protein 164
    Names
    CG9170-PA
    CG9170-PB
    CG9170-PC
    Cep164-PA
    Cep164-PB
    Cep164-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15977967..15982944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298383.1 → NP_001285312.1  centrosomal protein 164, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285312.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXK9
      Conserved Domains (3) summary
      pfam00397
      Location:83 → 113
      WW; WW domain
      pfam08598
      Location:534 → 643
      Sds3; Sds3-like
      pfam15665
      Location:508 → 677
      FAM184; Family with sequence similarity 184, A and B

    2. NM_206753.3 → NP_996476.1  centrosomal protein 164, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996476.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXK9
      Conserved Domains (3) summary
      pfam00397
      Location:83 → 113
      WW; WW domain
      pfam08598
      Location:534 → 643
      Sds3; Sds3-like
      pfam15665
      Location:508 → 677
      FAM184; Family with sequence similarity 184, A and B

    3. NM_132867.3 → NP_573095.1  centrosomal protein 164, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573095.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXK9
      Related
      FBpp0073951
      Conserved Domains (3) summary
      pfam00397
      Location:83 → 113
      WW; WW domain
      pfam08598
      Location:534 → 643
      Sds3; Sds3-like
      pfam15665
      Location:508 → 677
      FAM184; Family with sequence similarity 184, A and B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXK9 Q9VXK9

    Gene LinkOut

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