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    Sfi1 SFI1 centrin binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305467, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sfi1provided by RGD
    Official Full Name
    SFI1 centrin binding proteinprovided by RGD
    Primary source
    RGD:1560636
    See related
    EnsemblRapid:ENSRNOG00000018412 AllianceGenome:RGD:1560636
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560636
    Summary
    Predicted to enable phosphatase binding activity. Orthologous to human SFI1 (SFI1 centrin binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 53.7), Kidney (RPKM 53.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sfi1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (82215423..82272811, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (77990965..78048352, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (83341900..83412733, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit epsilon, mitochondrial-like Neighboring gene proline rich 14-like Neighboring gene phosphatidylserine decarboxylase Neighboring gene uncharacterized LOC134481863 Neighboring gene eukaryotic translation initiation factor 4E nuclear import factor 1 Neighboring gene small nuclear ribonucleoprotein polypeptide G, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Docking motif-guided mapping of the interactome of protein phosphatase-1. Hendrickx A, et al. Chem Biol, 2009 Apr 24. PMID 19389623
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables phosphatase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein SFI1 homolog
    Names
    Sfi1 homolog, spindle assembly associated

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191682.1 → NP_001178611.1  protein SFI1 homolog

      See identical proteins and their annotated locations for NP_001178611.1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I5ZPC0, D3ZTG6
      Related
      ENSRNOP00000037698.5, ENSRNOT00000036848.8
      Conserved Domains (1) summary
      pfam08457
      Location:214 → 805
      Sfi1; Sfi1 spindle body protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      82215423..82272811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091999.2 → XP_038947927.1  protein SFI1 homolog isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZPC0
      Conserved Domains (2) summary
      TIGR02169
      Location:1109 → 1202
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam08457
      Location:323 → 805
      Sfi1; Sfi1 spindle body protein

    2. XM_063273185.1 → XP_063129255.1  protein SFI1 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZPC0, D3ZTG6

    3. XM_039092000.2 → XP_038947928.1  protein SFI1 homolog isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZPC0
      Conserved Domains (1) summary
      pfam08457
      Location:323 → 805
      Sfi1; Sfi1 spindle body protein

    4. XM_039092001.2 → XP_038947929.1  protein SFI1 homolog isoform X4

      Conserved Domains (1) summary
      pfam08457
      Location:323 → 809
      Sfi1; Sfi1 spindle body protein

    RNA

    1. XR_001841023.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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