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    Isoc1 isochorismatase domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66307, updated on 9-Dec-2024

    Summary

    Official Symbol
    Isoc1provided by MGI
    Official Full Name
    isochorismatase domain containing 1provided by MGI
    Primary source
    MGI:MGI:1913557
    See related
    Ensembl:ENSMUSG00000024601 AllianceGenome:MGI:1913557
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610034N03Rik
    Summary
    Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human ISOC1 (isochorismatase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 28.1), genital fat pad adult (RPKM 26.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Isoc1 in Genome Data Viewer
    Location:
    18 D3; 18 33.71 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (58792554..58812642)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (58659482..58679570)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44701 Neighboring gene solute carrier family 27 (fatty acid transporter), member 6 Neighboring gene predicted gene, 23270 Neighboring gene STARR-seq mESC enhancer starr_44702 Neighboring gene STARR-seq mESC enhancer starr_44704 Neighboring gene predicted gene, 57652 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 19 Neighboring gene STARR-seq mESC enhancer starr_44705 Neighboring gene ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    isochorismatase domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025478.3NP_079754.2  isochorismatase domain-containing protein 1

      See identical proteins and their annotated locations for NP_079754.2

      Status: PROVISIONAL

      Source sequence(s)
      AC158924
      Consensus CDS
      CCDS29265.1
      UniProtKB/Swiss-Prot
      Q3U677, Q91V64
      UniProtKB/TrEMBL
      A0A494B952
      Related
      ENSMUSP00000025503.9, ENSMUST00000025503.10
      Conserved Domains (1) summary
      cd01012
      Location:115269
      YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      58792554..58812642
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)