Ceacam10 CEA cell adhesion molecule 10 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ceacam10provided by MGI
Official Full Name: CEA cell adhesion molecule 10provided by MGI
Primary source: MGI:MGI:1347248
See related: Ensembl:ENSMUSG00000054169 AllianceGenome:MGI:1347248
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Bgp3; Cea10
Summary: Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in regulation of immune system process and signal transduction. Predicted to be located in extracellular region. Predicted to be active in cell surface and plasma membrane. Is expressed in several structures, including alimentary system; immune system; reproductive system; and submandibular gland primordium. [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in genital fat pad adult (RPKM 164.8), colon adult (RPKM 46.0) and 3 other tissues See more
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Genomic context

Location:: 7 A3; 7 12.78 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (24476592..24484081)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (24777167..24784656)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The purification and physiological role of CEACAM10 in male mice is reported. [CEACAM]
Title: Demonstration of a glycoprotein derived from the Ceacam10 gene in mouse seminal vesicle secretions.
Taken together, both Ceacam10 and Ceacam9, alone or in combination, are not essential for either murine placental and embryonic development or for adult life.
Title: Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)
Targeted (2) 1 citation

General gene information

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Markers

L38422 (e-PCR)
- UniSTS:159614

Ceacam10 (e-PCR), detects polymorphism
- UniSTS:507358

L38422 (e-PCR)
- UniSTS:124907

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein tyrosine kinase binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of immune system process	IBA Inferred from Biological aspect of Ancestor more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cell surface	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: carcinoembryonic antigen-related cell adhesion molecule 10

Names: CEA-related cell adhesion molecule 10; carcinoembryonic antigen 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001374785.1 → NP_001361714.1 carcinoembryonic antigen-related cell adhesion molecule 10 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

AC161488

Consensus CDS

CCDS90181.1

UniProtKB/TrEMBL

A0A0U1RQ24

Related

ENSMUSP00000146217.2, ENSMUST00000206847.2

Conserved Domains (1) summary

cd05774
Location:36 → 140

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
NM_007675.4 → NP_031701.3 carcinoembryonic antigen-related cell adhesion molecule 10 isoform 1 precursor

See identical proteins and their annotated locations for NP_031701.3

Status: VALIDATED

Source sequence(s)

AC161488, AK018529, BE949028

Consensus CDS

CCDS39833.1

UniProtKB/Swiss-Prot

Q61400, Q99LD6, Q9D329

UniProtKB/TrEMBL

A0A0R4J0G1

Related

ENSMUSP00000037036.8, ENSMUST00000038069.9

Conserved Domains (1) summary

cd05774
Location:36 → 140

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

24476592..24484081

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030242605.2 → XP_030098465.1 carcinoembryonic antigen-related cell adhesion molecule 10 isoform X1

Conserved Domains (1) summary

cd05774
Location:32 → 136

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)