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    Osi19 Osiris 19 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40776, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Osi19provided by FlyBase
    Official Full Name
    Osiris 19provided by FlyBase
    Primary source
    FLYBASE:FBgn0037429
    Locus tag
    Dmel_CG15189
    See related
    AllianceGenome:FB:FBgn0037429
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15189; Dmel\CG15189; osi19
    Summary
    Involved in open tracheal system development. Located in endosome membrane. Is expressed in embryonic/larval tracheal dorsal trunk; embryonic/larval tracheal transverse connective; and larval tracheal system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Osi19 in Genome Data Viewer
    Location:
    83E4-83E4; 3-47.5 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6335362..6337196)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2161084..2162918)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Osiris 17 Neighboring gene Osiris 18 Neighboring gene Osiris 20 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An Ichor-dependent apical extracellular matrix regulates seamless tube shape and integrity. Rosa JB, et al. PLoS Genet, 2018 Jan. PMID 29309404, Free PMC Article
    2. The Osiris family genes function as novel regulators of the tube maturation process in the Drosophila trachea. Scholl A, et al. PLoS Genet, 2023 Jan. PMID 36689473, Free PMC Article
    3. Tracheal expression of Osiris gene family in Drosophila. Scholl A, et al. Gene Expr Patterns, 2018 Jun. PMID 29548969
    4. Osiris gene family defines the cuticle nanopatterns of Drosophila. Sun Z, et al. Genetics, 2024 Jun 5. PMID 38652268, Free PMC Article
    5. Conserved roles of Osiris genes in insect development, polymorphism and protection. Smith CR, et al. J Evol Biol, 2018 Apr. PMID 29322640

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in open tracheal system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    osiris 19
    Names
    CG15189-PA
    CG15189-PB
    Osi19-PA
    Osi19-PB
    osiris

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6335362..6337196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141383.2 → NP_649640.1  osiris 19, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649640.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI06
      Related
      FBpp0081204
      Conserved Domains (2) summary
      pfam07898
      Location:57 → 163
      DUF1676; Protein of unknown function (DUF1676)
      pfam12420
      Location:152 → 216
      DUF3671; Protein of unknown function

    2. NM_001170058.2 → NP_001163529.1  osiris 19, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163529.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWK7
      Conserved Domains (1) summary
      pfam07898
      Location:57 → 162
      DUF1676; Protein of unknown function (DUF1676)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AWK7 Q6AWK7
    Q9VI06 Q9VI06

    Gene LinkOut

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