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    CG13318 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41048, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13318provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037627
    Locus tag
    Dmel_CG13318
    See related
    AllianceGenome:FB:FBgn0037627
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    c-SPH101; cSPH101; Dmel\CG13318; Dmel_CG13318; SPH101
    Summary
    Predicted to be involved in innate immune response. Predicted to be active in extracellular space. Is expressed in embryonic antennal sense organ; embryonic central brain; embryonic head sensory system; seminal receptacle; and sensory cluster. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13318 in Genome Data Viewer
    Location:
    85B1-85B1; 3-48 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8771246..8772691, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4596968..4598413, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44228 Neighboring gene Nuclear autoantigenic sperm protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene PFTAIRE-interacting factor 1B Neighboring gene PFTAIRE-interacting factor 1A Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PFTAIRE Kinase L63 Interactor 1A (Pif1A Protein) Is Required for Actin Cone Movement during Spermatid Individualization in Drosophila melanogaster. Pravder HD, et al. Int J Mol Sci, 2022 Mar 10. PMID 35328431, Free PMC Article
    2. Age-dependent changes in the transcription profile of long-lived Drosophila over-expressing glutamate cysteine ligase. Radyuk SN, et al. Mech Ageing Dev, 2012 Jun. PMID 22579812
    3. Transcriptional profiling of the sperm storage organs of Drosophila melanogaster. Prokupek AM, et al. Insect Mol Biol, 2009 Aug. PMID 19453766
    4. Drosophila melanogaster clip-domain serine proteases: Structure, function and regulation. Veillard F, et al. Biochimie, 2016 Mar. PMID 26453810
    5. Temporally variable selection on proteolysis-related reproductive tract proteins in Drosophila. Wong A, et al. Mol Biol Evol, 2012 Jan. PMID 21940639, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    NOT enables serine-type endopeptidase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13318-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8771246..8772691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141574.4 → NP_649831.1  uncharacterized protein Dmel_CG13318 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649831.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZ60, Q9VHL8
      Related
      FBpp0081424
      Conserved Domains (2) summary
      smart00020
      Location:169 → 399
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:169 → 402
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZ60 Q8SZ60

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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