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    ketose-bisphosphate aldolase class-II family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838407, updated on 18-Sep-2024

    Summary

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    Official Full Name
    ketose-bisphosphate aldolase class-II family protein
    Primary source
    TAIR:AT1G18270
    Locus tag
    AT1G18270
    See related
    Araport:AT1G18270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10O22.24; T10O22_24
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    42
    Sequence:
    Chromosome: 1; NC_003070.9 (6283370..6293993, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HCP-like superfamily protein Neighboring gene zein-binding protein (Protein of unknown function, DUF593) Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene DUF4228 domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
    2. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001123831.1
    NM_001198099.1
    NM_001332339.1
    NM_101685.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aldehyde-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ketose-bisphosphate aldolase class-II family protein
    NP_001117303.1
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001185028.1
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1).
    NP_173263.2
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 34046 Blast hits to 22505 proteins in 2700 species: Archae - 264; Bacteria - 21742; Metazoa - 568; Fungi - 820; Plants - 423; Viruses - 1; Other Eukaryotes - 10228 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6283370..6293993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101685.5 → NP_173263.2  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, A0A654ECE6, Q8VYC5
      Conserved Domains (1) summary
      PLN02858
      Location:1 → 1373
      PLN02858; fructose-bisphosphate aldolase

    2. NM_001332339.1 → NP_001322878.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVD8, A0A5S9UZZ2

    3. NM_001123831.1 → NP_001117303.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, B3H739
      Conserved Domains (7) summary
      PLN02858
      Location:1 → 1374
      PLN02858; fructose-bisphosphate aldolase
      pfam01116
      Location:1098 → 1373
      F_bP_aldolase; Fructose-bisphosphate aldolase class-II
      pfam03446
      Location:324 → 484
      NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
      pfam07005
      Location:656 → 894
      DUF1537; Putative sugar-binding N-terminal domain
      pfam14833
      Location:489 → 609
      NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
      pfam17042
      Location:918 → 1084
      DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
      cl21454
      Location:5 → 158
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. NM_001198099.1 → NP_001185028.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, F4IAP5
      Conserved Domains (7) summary
      PLN02858
      Location:1 → 1393
      PLN02858; fructose-bisphosphate aldolase
      pfam01116
      Location:1117 → 1392
      F_bP_aldolase; Fructose-bisphosphate aldolase class-II
      pfam03446
      Location:323 → 483
      NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
      pfam07005
      Location:655 → 913
      DUF1537; Putative sugar-binding N-terminal domain
      pfam14833
      Location:488 → 608
      NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
      pfam17042
      Location:937 → 1103
      DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
      cl21454
      Location:5 → 157
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version

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