U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG15814 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32765, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG15814provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030873
    Locus tag
    Dmel_CG15814
    See related
    AllianceGenome:FB:FBgn0030873
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15814
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in ERAD pathway. Predicted to be active in Golgi membrane and endoplasmic reticulum membrane. Is expressed in several structures, including adult head; embryonic/larval midgut; embryonic/larval midgut primordium; gland; and salivary gland body primordium. Orthologous to human RNF121 (ring finger protein 121) and RNF175 (ring finger protein 175). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG15814 in Genome Data Viewer
    Location:
    16E1-16E1; 1-59 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (17848110..17850342, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17742143..17744375, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44691 Neighboring gene uncharacterized protein Neighboring gene TBP-associated factor 9 Neighboring gene uncharacterized protein Neighboring gene Uncoupling protein 4A Neighboring gene Spt7 Neighboring gene uncharacterized protein Neighboring gene Multicopper oxidase 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila. Landry CR, et al. Genetics, 2005 Dec. PMID 16143608, Free PMC Article
    2. Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model. Park JE, et al. Exp Mol Med, 2023 Jul. PMID 37464094, Free PMC Article
    3. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article
    4. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
    5. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG15814-PA
    CG15814-PB
    CG15814-PC
    CG15814-PD

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      17848110..17850342 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167577.3 → NP_728098.1  uncharacterized protein Dmel_CG15814, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728098.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SS4, Q9VX13
      Related
      FBpp0074242
      Conserved Domains (1) summary
      pfam13639
      Location:218 → 270
      zf-RING_2; Ring finger domain

    2. NM_167578.3 → NP_728099.1  uncharacterized protein Dmel_CG15814, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728099.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SS4, Q9VX13
      Related
      FBpp0074244
      Conserved Domains (1) summary
      pfam13639
      Location:218 → 270
      zf-RING_2; Ring finger domain

    3. NM_133019.4 → NP_573247.2  uncharacterized protein Dmel_CG15814, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573247.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95SS4, Q9VX13
      Related
      FBpp0074243
      Conserved Domains (1) summary
      pfam13639
      Location:218 → 270
      zf-RING_2; Ring finger domain

    4. NM_167579.2 → NP_728100.1  uncharacterized protein Dmel_CG15814, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728100.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQZ5, Q95SS4
      Related
      FBpp0074245
      Conserved Domains (1) summary
      pfam13639
      Location:198 → 250
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQZ5 Q8IQZ5
    Q95SS4 Q95SS4
    Q9VX13 Q9VX13

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools