Utp15 UTP15 small subunit processome component [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Utp15provided by MGI
Official Full Name: UTP15 small subunit processome componentprovided by MGI
Primary source: MGI:MGI:2145443
See related: Ensembl:ENSMUSG00000041747 AllianceGenome:MGI:2145443
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be involved in positive regulation of RNA metabolic process and ribosome biogenesis. Predicted to be located in endoplasmic reticulum and fibrillar center. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP15 (UTP15 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 7.4), placenta adult (RPKM 5.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 13 D1; 13 51.87 cM

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	13	NC_000079.7 (98383353..98399500, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	13	NC_000079.6 (98246845..98262992, complement)

Chromosome 13 - NC_000079.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

NoName (e-PCR)
- UniSTS:237088

AW544865 (e-PCR)
- UniSTS:185982

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in positive regulation of rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of rRNA processing	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of transcription by RNA polymerase I	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase I	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of transcription by RNA polymerase I	ISO Inferred from Sequence Orthology more info
involved_in rRNA processing	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in ribosomal small subunit biogenesis	ISO Inferred from Sequence Orthology more info
involved_in ribosomal small subunit biogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in fibrillar center	ISO Inferred from Sequence Orthology more info
located_in fibrillar center	ISS Inferred from Sequence or Structural Similarity more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleolus	ISS Inferred from Sequence or Structural Similarity more info
part_of small-subunit processome	ISO Inferred from Sequence Orthology more info
part_of small-subunit processome	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: U3 small nucleolar RNA-associated protein 15 homolog

Names: UTP15, U3 small nucleolar ribonucleoprotein, homolog; src-associated protein SAW

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_178918.3 → NP_849249.1 U3 small nucleolar RNA-associated protein 15 homolog

See identical proteins and their annotated locations for NP_849249.1

Status: PROVISIONAL

Source sequence(s)

AC123056

Consensus CDS

CCDS26712.1

UniProtKB/Swiss-Prot

Q3TRG8, Q8C7V3, Q8K231

UniProtKB/TrEMBL

Q3TN42

Related

ENSMUSP00000048204.3, ENSMUST00000040972.4

Conserved Domains (4) summary

COG2319
Location:28 → 310

WD40; WD40 repeat [General function prediction only]

cd00200
Location:39 → 298

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

pfam09384
Location:343 → 487

UTP15_C; UTP15 C terminal

sd00039
Location:41 → 78

7WD40; WD40 repeat [structural motif]