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    CG11007 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37249, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11007provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034455
    Locus tag
    Dmel_CG11007
    See related
    AllianceGenome:FB:FBgn0034455
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11007
    Summary
    Predicted to enable disulfide oxidoreductase activity. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; ganglia; and mesoderm. Orthologous to human TMX2 (thioredoxin related transmembrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11007 in Genome Data Viewer
    Location:
    56D14-56D14; 2-89 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19503068..19504594)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15390573..15392099)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Rab escort protein Neighboring gene hippo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44472 Neighboring gene transfer RNA:Histidine-GTG 1-5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis reveals temporally regulated genetic networks during Drosophila border cell collective migration. Burghardt E, et al. BMC Genomics, 2023 Dec 1. PMID 38041052, Free PMC Article
    2. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article
    3. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
    4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables disulfide oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondria-associated endoplasmic reticulum membrane contact site ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11007-PA
    CG11007-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19503068..19504594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299688.1 → NP_001286617.1  uncharacterized protein Dmel_CG11007, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286617.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JW12
      UniProtKB/TrEMBL
      A0A0B4LFY2
      Conserved Domains (1) summary
      cd02962
      Location:100 → 251
      TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...

    2. NM_137585.4 → NP_611429.1  uncharacterized protein Dmel_CG11007, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611429.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JW12
      UniProtKB/TrEMBL
      A0A0B4LFY2
      Related
      FBpp0085660
      Conserved Domains (1) summary
      cd02962
      Location:100 → 251
      TMX2; TMX2 family; composed of proteins similar to human TMX2, a 372-amino acid TRX-related transmembrane protein, identified and characterized through the cloning of its cDNA from a human fetal library. It contains a TRX domain but the redox active CXXC motif ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LFY2 A0A0B4LFY2
    Q7JW12.1 Q7JW12

    Gene LinkOut

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