cbc crowded by cid [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: cbcprovided by FlyBase
Official Full Name: crowded by cidprovided by FlyBase
Primary source: FLYBASE:FBgn0033842
Locus tag: Dmel_CG5970
See related: AllianceGenome:FB:FBgn0033842
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Cbc; CBC; cg5970; CG5970; Dmel\CG5970
Summary: Predicted to enable ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity and ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to be part of tRNA-intron endonuclease complex. Predicted to be active in nucleus. Is expressed in organism. Used to study pontocerebellar hypoplasia type 10. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 10. Orthologous to human CLP1 (cleavage factor polyribonucleotide kinase subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (13483512..13485391, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (9371017..9372896, complement)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	ISS Inferred from Sequence or Structural Similarity more info
enables polynucleotide 5'-hydroxyl-kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables polynucleotide 5'-hydroxyl-kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mRNA 3'-end processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA splicing, via endonucleolytic cleavage and ligation	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA splicing, via endonucleolytic cleavage and ligation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of mRNA cleavage factor complex	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of tRNA-intron endonuclease complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain