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    UBS1 Ubs1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852463, updated on 9-Dec-2024

    Summary

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    Official Symbol
    UBS1
    Official Full Name
    Ubs1p
    Primary source
    SGD:S000000369
    Locus tag
    YBR165W
    See related
    AllianceGenome:SGD:S000000369; FungiDB:YBR165W; VEuPathDB:YBR165W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein export from nucleus and protein ubiquitination. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See UBS1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (568852..569685)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Exo5p Neighboring gene Arf family GTPase ARL1 Neighboring gene prephenate dehydrogenase (NADP(+)) Neighboring gene ribonuclease P/MRP protein subunit POP7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a positive regulator of the cell cycle ubiquitin-conjugating enzyme Cdc34 (Ubc3). Prendergast JA, et al. Mol Cell Biol, 1996 Feb. PMID 8552096, Free PMC Article
    2. Yeast Ran-binding protein Yrb1p is required for efficient proteolysis of cell cycle regulatory proteins Pds1p and Sic1p. Bäumer M, et al. J Biol Chem, 2000 Dec 8. PMID 10991951
    3. Histone modifications influence mediator interactions with chromatin. Zhu X, et al. Nucleic Acids Res, 2011 Oct. PMID 21742760, Free PMC Article
    4. Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. Chao JT, et al. Dev Cell, 2019 Oct 21. PMID 31564614, Free PMC Article
    5. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Magtanong L, et al. Nat Biotechnol, 2011 May 15. PMID 21572441, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ubs1p
    NP_009724.1
    • Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p; functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      568852..569685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178513.1 → NP_009724.1  TPA: Ubs1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009724.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQG1, P38290
      UniProtKB/TrEMBL
      A6ZLA8, B3LMZ3, B5VEC2, C7GUI0, D3UER0, G2W9G8, N1PAU2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38290.1

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