Lcn1 lipocalin 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lcn1provided by RGD
Official Full Name: lipocalin 1provided by RGD
Primary source: RGD:619872
See related: EnsemblRapid:ENSRNOG00000085594 AllianceGenome:RGD:619872
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Vegp1; Lcn1p1
Summary: Predicted to enable several functions, including chloride ion binding activity; identical protein binding activity; and zinc ion binding activity. Predicted to be involved in sensory perception of taste. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to several human genes including LCN1 (lipocalin 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 3.8), Thymus (RPKM 2.2) and 1 other tissue See more
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Genomic context

Location:: 3p13

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (29930943..29935418)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (9532860..9537859)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (4233111..4236960)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables chloride ion binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables signaling receptor binding	ISO Inferred from Sequence Orthology more info
enables small molecule binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in sensory perception of taste	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: von Ebner gland protein 1

Names: VEG protein 1; lipocalin 1 pseudogene 1; von Ebners gland protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_022945.2 → NP_075234.1 von Ebner gland protein 1 precursor

See identical proteins and their annotated locations for NP_075234.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/Swiss-Prot

P20289

UniProtKB/TrEMBL

A6JTH4, R9PXY4

Related

ENSRNOP00000043245.5, ENSRNOT00000041399.6

Conserved Domains (1) summary

cd19414
Location:26 → 173

lipocalin_1_3_4_13-like; lipocalin-1, -3, -4, -13 and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

29930943..29935418

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039105817.2 → XP_038961745.1 von Ebner gland protein 1 isoform X1

Conserved Domains (1) summary

cl10502
Location:1 → 100

lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family