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    CG12511 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33797, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12511provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031729
    Locus tag
    Dmel_CG12511
    See related
    AllianceGenome:FB:FBgn0031729
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12511
    Summary
    Predicted to be involved in autophagy of mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC1 (FUN14 domain containing 1) and FUNDC2 (FUN14 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12511 in Genome Data Viewer
    Location:
    25F2-25F2; 2-17 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5678582..5679499)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5678582..5679499)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44821 Neighboring gene Heat shock protein 60C Neighboring gene long non-coding RNA:CR44819 Neighboring gene long non-coding RNA:CR44820 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. Halfon MS, et al. Genome Res, 2002 Jul. PMID 12097338, Free PMC Article
    2. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial outer membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12511-PB
    CG12511-PC
    CG12511-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5678582..5679499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298704.1 → NP_001285633.1  uncharacterized protein Dmel_CG12511, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285633.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6IDP6
      Conserved Domains (1) summary
      pfam04930
      Location:13 → 109
      FUN14; FUN14 family

    2. NM_001258970.2 → NP_001245899.1  uncharacterized protein Dmel_CG12511, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245899.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6IDP6
      Conserved Domains (1) summary
      pfam04930
      Location:13 → 109
      FUN14; FUN14 family

    3. NM_135105.3 → NP_608949.2  uncharacterized protein Dmel_CG12511, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608949.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMN4
      Conserved Domains (1) summary
      pfam04930
      Location:23 → 119
      FUN14; FUN14 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B6IDP6 B6IDP6
    Q9VMN4 Q9VMN4

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